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临床试验/NCT05677165
NCT05677165已完成不适用

The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study

Bakirkoy Dr. Sadi Konuk Research and Training Hospital1 个研究点 分布在 1 个国家目标入组 361 人开始时间: 2020年3月18日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
361
试验地点
1
主要终点
In hospital mortality

研究概览

简要总结

By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot), Driving Pressure Saturation Index (OSIDP), Dynamic Power Saturation Index (OSIMPdyn) ve Power Saturation Index (OSIMPtot).

New oxygenation and saturation indices are able to predict ICU mortality better than the conventional indexes and rates.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients with a diagnosis of Covid-19 related Acute Respiratory Syndrome (C-ARDS) which hospitalized in Bakirköy Dr. Sadi Konuk Training and Research Hospital intensive care unit

排除标准

  • •Patients who did not receive invasive mechanical ventilation support.
  • •Patients who stayed in the intensive care unit for less than 24 hours.
  • •Patients with missing data
  • •Patients who received mechanical ventilation support for less than 24 hours
  • •Patients with Chronic Obstructive Pulmonary Disease (COPD).
  • •Patients with congestive heart failure
  • •Patients who underwent tube thoracostomy due to tension pneumothorax
  • •Patients who received Extracorporeal Membrane Oxygenation (ECMO) support

结局指标

主要结局

In hospital mortality

时间窗: 28 days

we estimate hospital mortality mortality by calculating new oxygenation index

次要结局

  • Mechanical ventilatory free days(30 days)

研究者

发起方
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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