NCT00149409已完成2 期
Omega-3-Polyunsaturated Fatty-Acids (N3-Pufa) In Patients With Severe Chronic Heart Failure:Effects On Endothelial Function, Left Ventricular Remodelling, Natriuretic Peptide Levels, And Exercise Capacity
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 试验地点
- 2
研究概览
简要总结
To investigate whether n3-fatty acids have beneficial effects in chronic heart failure as regards circulatory function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic heart failure of non-ischemic origin
- •Age ≥18 years
- •NYHA functional class III-IV
- •LVEF < 35 %
- •Optimized heart failure therapy
- •plasma NT-BNP >2000pg/ml
排除标准
- •Current treatment with Omacor or other fish oil products
- •Known hypersensitivity to the study drug
- •Ischemic cardiomyopathy
- •Uncorrected significant valvular heart disease
- •Heart failure due to congenital heart disease
- •Restrictive cardiomyopathy
- •Alcoholic heart disease
- •Acute myocarditis
- •Continuous i.v. therapy for heart failure
- •Mechanical assist device
- •Life expectancy <1 year due to non-cardiac causes
- •Inability to perform bicycle testing
- •Women of childbearing potential not practicing a save contraception method
- •Current participation in another intervention study
- •Participation in another study with an intervention within the last 3 months.
研究者
研究点 (2)
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