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临床试验/NCT03843411
NCT03843411撤回不适用

Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient

Changhua Christian Hospital0 个研究点开始时间: 2019年10月最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
主要终点
change of stroke volume index

研究概览

简要总结

The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum

详细描述

Perioperative fluid management is significant important during surgery. The current trend tends to use goal-directed fluid therapy in surgery. Goal-directed fluid therapy refers to continuous monitoring of hemodynamic parameters during surgery and managing more accurate fluid administration based on the data obtained while promoting optimal tissue perfusion. Define fluid responsiveness with the hemodynamic parameters as to whether the cardiac output can be significantly increased after administration of fluid. Therefore, the advantage of predicting fluid responsiveness is that it can optimize the cardiac output and tissue perfusion while avoiding administering unnecessary fluid to patients.

The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Prospective

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • receive operation that required pneumoperitoneum and FloTrac monitoring
  • age between 20 to 70 year old

排除标准

  • patient who cannot understand the process and aim of the study
  • patient with arrhythmia
  • poor heart function(LVEF<50%, severe valvular disease, CAD)
  • pregnant patient
  • patients allergic to voluven

结局指标

主要结局

change of stroke volume index

时间窗: 1 hours

record stroke volume index before and after mini-fluid challenge

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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