A study to evaluate the effect of dexmedetomidine on haemodynamic response in untreated stage1 hypertensive patients undergoing laproscopic cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To investigate effect of dexmedetomidine on hemodynamic response to laryngoscopy,intubation,pneumoperitoneum and extubation in stage 1 hypertensive patients undergoing laproscopic cholecystectomy
研究概览
简要总结
The present prospective study will be conducted in the depatment of anaesthesia and critical care,PGIMS,ROHTAK.Written informed consent will be taken from patients included.The study is to investigate the effect of dexemedetomidine on hemodynamic response in untreated stage1 hypertensive patients undergoing laproscopic cholecystectomy.The changes in HR & MAP during laryngoscopy,intubation,creation & release of pneumoperitonium and extubation will be noted.Data will be compiled and analysed with appropriate statistical test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Asa 1&2 Either sex Posted for laproscopic cholecystectomy Stage 1 hypertensive patients,not on any medication.
排除标准
- •Patients with difficult airway Stage 2 hypertensive Patients on antihypertensive medication Patients with cardiac,renal,hepatic or endocrine disease Pregnant or morbid obese Allergic to dexmedetomidine.
结局指标
主要结局
To investigate effect of dexmedetomidine on hemodynamic response to laryngoscopy,intubation,pneumoperitoneum and extubation in stage 1 hypertensive patients undergoing laproscopic cholecystectomy
时间窗: To investigate effect of dexmedetomidine on hemodynamic response to laryngoscopy,intubation,pneumoperitoneum 15 minutes,release of pneumoperitoneum and extubation in stage 1 hypertensive patients undergoing laproscopic cholecystectomy during perioperative period.
次要结局
- To observe time to extubate trachea,time to first rescue analgesia and post operative sedation score at 1 min, 15 minutes, 30 minutes and 60 minutes.(Any adverse effects like hypotension,bradycardia and excessive sedation during perioperative period and sedation score at 1 minute, 15 minute,30 minutes and 60 minutes.)