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临床试验/EUCTR2014-003965-11-NL
EUCTR2014-003965-11-NL进行中(未招募)不适用

Targeted therapy with Imatinib for treatment of poor prognosis mesenchymal-type resectable colon cancer: a proof-of-concept study in the preoperative window period. - ImPACT

niversity Medical Center Utrecht0 个研究点开始时间: 2015年9月15日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • 1. Histologically proven adenocarcinoma of the colon;
  • 2. Confirmed eligibility for surgery with curative intent as deemed by the hospital’s multidisciplinary team (MDT) review;
  • 3. High intratumoural gene expression of PDGFR-a, PDGFR-ß, PDGF-C and KIT according to our diagnostic RT-qPCR test.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 27
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 27

排除标准

  • The presence of synchronous distant metastases;
  • Current hospital standard of care dictates that patient should undergo any neoadjuvant therapy;
  • Concurrent participation in another clinical trial using any medicinal product, or participation in such a trial in the period of three months prior to the current trial;

研究者

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