Comparitive study between ropivacaine plus dexmedetomidine versus ropivacaine plus magnesium sulfate in ultrasound guided transversus abdominis plane block “TAP†in post operative pain management after laproscopic nephrectomy
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- post operative pain relief(visual analogue scale scale)
研究概览
简要总结
Laparoscopic nephrectomyis one of the commonly performed surgical procedures that is associated with amoderate degree of postoperative pain especially on the 1st postoperativeday. Adequate postoperative analgesia allows early patient ambulation, decreasesanalgesic requirements, and hospital length of stay. Ultrasoundguided Transversus abdominis plane (TAP) block is a recentanalgesic technique that has proved its efficacyin perioperative pain therapy for Laparoscopic nephrectomy surgery.Theaim of this study will be to compare additionof dexmedetomidine to ropivacaine versus magnesium sulfateto ropivacaine in ultrasound guided TAP block on postoperative painscores (primary outcome) , time to first rescue analgesia, total analgesicrequirement and postoperative nausea and vomiting (PONV) (secondary outcomes)in the patients undergoing Laparoscopic nephrectomy surgery .
The aim of this study will be to compareaddition of dexmedetomidine to ropivacaine versusmagnesium sulfate to ropivacaine in ultrasound guided TAP blockon postoperative pain scores (primary outcome) , time to first rescueanalgesia, total analgesic requirement and postoperative nausea and vomiting(PONV) (secondary outcomes) in the patients undergoing Laparoscopic nephrectomysurgery .
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •â€“ patients undergoing laproscopic nephrectomy ( simple , radical , donor ) between age group 18- 60 years , patients with ASA ( American society of anesthesiology) grade 1 and I1.
排除标准
- •Patients not willing, patient’s age below18 and above 60 years, with deranged coagulation profile, with infection at the site of block, with allergy to any of the drugs to be used in study, and patients with severe cardio respiratory disease will be excluded from the study.
结局指标
主要结局
post operative pain relief(visual analogue scale scale)
时间窗: immidiate postoperative period and in recovery and step down recovery room.
次要结局
- nausea , vomiting(post operative period)