Clinical and Radiographic Assessment of Apical Periodontitis with Calcium Hydroxide vs Triple Antibiotic Paste Both when used along with Chlorhexidine Digluconate as Vehicle : A Randomized Controlled Trial
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The primary objective will focus on
研究概览
简要总结
Patients will be randomly assigned to two groups:
• Group A: Calcium Hydroxide + 2% Chlorhexidine Digluconate
• Group B: Triple Antibiotic Paste + 2% Chlorhexidine Digluconate
Procedure:
• Patients will undergo endodontic treatment with intracanal medicaments.
• Standard protocol will be followed, including anesthesia (2% lignocaine with 1:80,000 adrenaline), rubber dam isolation, caries excavation, access opening, and root canal preparation using Ni-Ti rotary files.
• Canals will be irrigated with sodium hypochlorite, normal saline, and 17% EDTA, then dried with sterile paper points.
Intracanal Medication Protocol:
• Step I: Intracanal medicament applied, changed after 7 days.
• Step II: Medication retained for another 7 days.
• After 15 days, the master cone will be selected, and the canals will be obturated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult Patients aged between 18 and 45 years.
- •Single-rooted teeth (anterior and posterior).
- •Teeth with Apical periodontitis.
- •Teeth with necrotic pulp that gave a negative response to vitality testing.
排除标准
- •Non-restorable teeth.
- •Teeth requiring retreatment.
- •Teeth with calcified canals.
- •Teeth with internal/external root resorption.
- •Patients with serious medical illness.
- •Patients with known allergies to the materials used in the study.
结局指标
主要结局
The primary objective will focus on
时间窗: at the interval of 1 month, 3 months and 6 months
periapical healing
时间窗: at the interval of 1 month, 3 months and 6 months
次要结局
- Postoperative pain will be assessed as a secondary(outcome.)
研究者
Dr Harnoor
Deaprtment of Conservative Dentistry and Endodontics Himachal Dental College Sundernagar