NCT01670747已完成不适用
Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Patients With Acute Respiratory Distress Syndrome
Policlinico Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2012年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Computer Tomography (CT) scan lung recruitment and CT lung weight
研究概览
简要总结
In this study gas-exchange and respiratory mechanics variations to PEEP change will be correlated to CT lung morphological modifications assessed at different airway pressures (5, 15, 30 and 45 cmH2O).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of acute lung injury/ acute respiratory distress syndrome
- •Mechanical ventilation
排除标准
- •Clinical diagnosis of chronic obstructive pulmonary disease
- •Clinical diagnosis of pneumothorax
- •Haemodynamic instability
结局指标
主要结局
Computer Tomography (CT) scan lung recruitment and CT lung weight
时间窗: Study day (day 1)
Aim of the study is to determine the relationship between the opening pressures (recruitment) and closing pressures (PEEP) in order to prevent the opening and closing of the lung parenchyma
次要结局
未报告次要终点
研究者
Davide Chiumello
MD
Policlinico Hospital
研究点 (1)
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