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临床试验/NCT06272435
NCT06272435已完成不适用

Beverage Hydration Index: Assessment of Four Rehydration Solutions

University of Memphis2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2023年12月23日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
28
试验地点
2
主要终点
Beverage Hydration Index

研究概览

简要总结

No studies to date to evaluate the effects of the three different liquid IV electrolyte products on the beverage hydration index (BHI). Therefore, the purpose of this study is to determine the impact of three different LIV products (Hydration multiplier, Sugar Free formulation with Amino Acids, and Sugar Free with allulose) on hydration status in young and active men and women compared to a control (water). The study will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and BHI (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance, as well as determining electrolyte concentrations, osmolality, specific gravity, and sodium and potassium in urine.

详细描述

Many attempts have been made to improve and measure the hydration status of active individuals. This typically involves the ingestion of fluids leading up to activity (typically plain water), as well as the ingestion of fluids during the activity itself (water, along with a diluted carbohydrate/electrolyte beverage). This approach seems to work well; however, some debate remains over what the best fluid is to consume, in particular related to the macronutrient type and the specific electrolyte mix.

No studies to date to evaluate the effects of the three different liquid IV electrolyte products on the beverage hydration index (BHI). Therefore, the purpose of this study is to determine the impact of three different LIV products (Hydration multiplier, Sugar Free formulation with Amino Acids, and Sugar Free with allulose) on hydration status in young and active men and women compared to a control (water). The study will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and BHI (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance, as well as determining electrolyte concentrations, osmolality, specific gravity, and sodium and potassium in urine.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

盲法说明

Treatments will be labeled A-D. Subjects will be provided prepared beverages prepared in cup.

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • body mass index (BMI) <35 kilgrams per square meter
  • consistent dietary intake and exercise throughout study period
  • consumes 2 liters (women) or 2.5 liters (men) of water per day prior to study visits
  • able to fast for 15 hours

排除标准

  • sensitivity or be allergic to any components of the study product they will be excluded.
  • tobacco user
  • specialized diet (low carbohydrate/ketogenic diet, carnivore diet, intermittent fasting, etc.)
  • caffeine consumption within 12 hours of study visit
  • strenuous activity within 24 hours of study visit
  • history or presence of a clinically relevant (that required or requires treatment) cardiac, renal, hepatic, endocrine (including diabetes mellitus), pulmonary, biliary, gastrointestinal, pancreatic, or neurologic disorder
  • conditions that alter fluid balance or electrolytes/hydration status
  • consuming any medication which may alter fluid retention/electrolyte levels such as sodium-glucose co-transporter 2 (SGLT2) inhibitor (for type 2 diabetes), laxatives, diuretics, Apremilast, chemotherapy, or lithium.
  • consuming nutritional supplements, performance enhancing drugs, and/or non-steroidal anti-inflammatory drugs within 7 days of study visits excluding screening).
  • employee of Liquid IV
  • be enrolled in another clinical study within 30 days of the first study visit
  • active infection or illness of any kind

研究组 & 干预措施

Water, Multiplier, Sugar Free, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Water, Sugar with Amino Acids, Sugar Free, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Water, Sugar with Amino Acids, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Multiplier, Water, Sugar Free, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Sugar with Amino Acids, Sugar Free, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Multiplier, Sugar Free, Sugar with Amino Acids, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Sugar Free, Sugar with Amino Acids, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar with Amino Acids, Multiplier, Water, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar with Amino Acids, Multiplier, Sugar Free, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Water, Multiplier, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar Free, Water, Sugar with Amino Acids, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar Free, Sugar with Amino Acids, Multiplier, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Water, Multiplier, Sugar with Amino Acids, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Water, Multiplier, Sugar with Amino Acids, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Water, Multiplier, Sugar with Amino Acids, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Water, Multiplier, Sugar Free, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Water, Multiplier, Sugar Free, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Water, Sugar with Amino Acids, Multiplier, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Water, Sugar with Amino Acids, Multiplier, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Water, Sugar with Amino Acids, Multiplier, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Water, Sugar with Amino Acids, Sugar Free, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Water, Sugar with Amino Acids, Sugar Free, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Water, Sugar Free, Multiplier, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Water, Sugar Free, Multiplier, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Water, Sugar Free, Multiplier, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Water, Sugar Free, Sugar with Amino Acids, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Water, Sugar Free, Sugar with Amino Acids, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Water, Sugar Free, Sugar with Amino Acids, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Multiplier, Water, Sugar with Amino Acids, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Water, Sugar with Amino Acids, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Multiplier, Water, Sugar Free, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Multiplier, Water, Sugar Free, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Multiplier, Sugar with Amino Acids, Water, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Sugar with Amino Acids, Water, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Multiplier, Sugar with Amino Acids, Water, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Multiplier, Sugar with Amino Acids, Sugar Free, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Sugar with Amino Acids, Sugar Free, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Multiplier, Sugar Free, Water, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Multiplier, Sugar Free, Water, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Multiplier, Sugar Free, Water, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Multiplier, Sugar Free, Sugar with Amino Acids, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Water, Multiplier, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar with Amino Acids, Water, Multiplier, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Water, Multiplier, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar with Amino Acids, Water, Sugar Free, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar with Amino Acids, Water, Sugar Free, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Water, Sugar Free, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar with Amino Acids, Multiplier, Water, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Multiplier, Water, and Sugar Free

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar with Amino Acids, Multiplier, Sugar Free, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar with Amino Acids, Multiplier, Sugar Free, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Sugar Free, Water, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar with Amino Acids, Sugar Free, Water, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Sugar Free, Water, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar with Amino Acids, Sugar Free, Multiplier, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar with Amino Acids, Sugar Free, Multiplier, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar with Amino Acids, Sugar Free, Multiplier, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Water, Multiplier, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar Free, Water, Multiplier, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Water, Sugar with Amino Acids, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar Free, Water, Sugar with Amino Acids, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Multiplier, Water, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar Free, Multiplier, Water, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar Free, Multiplier, Water, and Sugar with Amino Acids

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Multiplier, Sugar with Amino Acids, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar Free, Multiplier, Sugar with Amino Acids, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar Free, Multiplier, Sugar with Amino Acids, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Sugar with Amino Acids, Water, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar Free, Sugar with Amino Acids, Water, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

Sugar Free, Sugar with Amino Acids, Water, and Multiplier

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free with Amino Acids (Dietary Supplement)

Sugar Free, Sugar with Amino Acids, Multiplier, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Multiplier (Dietary Supplement)

Sugar Free, Sugar with Amino Acids, Multiplier, and Water

Experimental

Subjects will follow control diet for 24 hours prior to visit. At the study visit, baseline measures will be collected prior to treatment. Subjects will then consume the assigned treatment (one treatment per visit in order above) and additional experimental measurements will be collected.

干预措施: Sugar Free (Dietary Supplement)

结局指标

主要结局

Beverage Hydration Index

时间窗: 240 minutes after beverage consumption

Beverage Hydration index calculated as mass of urine collected following control (water) consumption divided by the mass of urine collected following treatment.

次要结局

  • Urine Specific Gravity(240 minutes after beverage consumption urine)
  • Sodium balance(240 minutes after beverage consumption)
  • Body Mass(240 minutes after beverage consumption)
  • Net Fluid Balance(240 minutes after beverage consumption)
  • Mood and Digestive Questionnaire(240 minutes after beverage consumption)
  • Urine Potassium(240 minutes after beverage consumption)
  • Urine Sodium(240 minutes after beverage consumption)
  • Potassium balance(240 minutes after beverage consumption)
  • Urine Osmolality(240 minutes after beverage consumption)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Bloomer

Dean of College of Health Sciences

University of Memphis

研究点 (2)

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