The Effect of Oral Dexmedetomidine Premedication On Preoperative Cooperation and Emergence Delirium In Children Undergoing Dental Treatment
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Ramsey Sedation Score
研究概览
简要总结
The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.
详细描述
One Hundred children between the ages 2-6 years of ASA I status underwent full mouth dental rehabilitation were enrolled in the study. Group Dex (n=50) received 1µg/kg dexmedetomidine in apple juice and Group control (n=50) received apple juice only. Patients' Ramsey Sedation Scale (RSS), The Parental Seperation Anxiety Scale (PSAS), Mask Acceptance Scale (MAS) and Post anesthesia emergence delirium scale (PAEDS) and hemodynamic parameters were noted from their patient file. Premedication period was 45 minutes and measurements of RSS and hemodynamic parameters were recorded in baseline and every 15 minutes until the patients were transferred to the operating room. The data were analysed using the Kruskal-Wallis test, two sample t- tests, chi-square tests and ANOVA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
盲法说明
Investigator
入排标准
- 年龄范围
- 2 Years 至 6 Years（Child）
- 接受健康志愿者
- 是
入选标准
- •The inclusion criteria is age between 2 to 6 years and American Society og Anesthesiology (ASA) grade 1.
排除标准
- •The exclusion criteria included congenital disease, DEX, propofol allergy, asthma, mental retardation and those children parents refuse to participate study.
研究组 & 干预措施
Control
Apple juice
干预措施: apple juice (Other)
Dexmedetomidine
Group administered 1µg/kg dexmedetomidine oral
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
Ramsey Sedation Score
时间窗: 45 minutes after premedication
Sedation level
次要结局
- Parental Separation Anxiety Score(preoperative)
研究者
SULTAN KELES
Assist. Prof.Dr.
Aydin Adnan Menderes University