Among Australians who have Diagnostic and Statistical Manual Fourth Edition(DSM IV) alcohol dependence or alcohol abuse, has thiamine supplementation of flour resulted in higher median serum thiamine concentrations than the normal population median reference range thus achieving the planned outcome of reducing the risk of Wernicke-Korsakoff syndrome in Australians.

Dr Philip Crowley, M.B.B.S., F.R.A.C.G.P., Grad. Dip. Mgt., Trainee R.A.C.P. Chapter of Addiction Medicine, Senior Medical Officer, Drug and Alcohol Services South Australia0 个研究点目标入组 180 人开始时间: 2010年8月13日最近更新: 2020年1月13日

适应症

试验速览

阶段: 未知
状态: 招募中
发起方
入组人数: 180

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Observational

入排标准

年龄范围: 18 Years 至 65 Years（—）
性别: All

入选标准

•Selection Criteria
•1.Require assessment for DSM IV Alcohol Dependence by the Driver Assessment Clinic of Drug and Alcohol Services South Australia as a result of multiple driving under the influence of alcohol convictions
•2.Able to provide a valid consent to participate in the study

排除标准

•1.Those who have had the surgical procedures: gastrectomy, gastrojejunostomy, partial or total colectomy, gastric bypasses surgery, vertical banded gastroplastyor obesity therapy with an intragastric balloon.
•2.Patients who have had recurrent vomiting or chronic diarrhoea resulting from anorexia nervosa, pancreatitis and hyperemnesis gravidarum.
•3.Those who have had the following cancer and related conditions: gastric or colon carcinoma, non Hodgkin’s lymphoma, myelomonocitic leukaemia, large B cell lymphoma, myeloid leukaemia, allogenic bone marrow transplantation, acquired immune deficiency syndrome.
•4.Those who have renal disease requiring dialysis.
•5.Magnesium depletion can result from chronic diuretic therapy, intestinal tract resection and Crohn’s disease. Patients with these conditions would be excluded from this aspect of the study

研究者

发起方

Dr Philip Crowley, M.B.B.S., F.R.A.C.G.P., Grad. Dip. Mgt., Trainee R.A.C.P. Chapter of Addiction Medicine, Senior Medical Officer, Drug and Alcohol Services South Australia

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