临床试验/CTRI/2020/12/029814

CTRI/2020/12/029814已完成不适用

Nintedanib Vs Pirfenidone in management of Covid19 related lung abnormality

PRATIMA SINGH1 个研究点分布在 1 个国家目标入组 30 人开始时间: 2020年12月16日最近更新: 2021年2月6日

试验速览

阶段: 不适用
状态: 已完成
发起方: PRATIMA SINGH
入组人数: 30
试验地点: 1
主要终点: Improvement in CT-severity score

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

NINTEDANIB AND PIRFENIDONE HAVE PROVEN ANTI FIBROTIC PROPERTIES AS SEEN IN THEIR ROLE IN TREATMENT OF IDIOPATHIC INTERSTITIAL FIBROSIS. COVID 19 ALSO LEADS TO LUNG FIBROSIS AND OXYGEN DEPENDENCY.THE MANAGEMENT OF COVID RELATED LUNG FIBROSIS SHOULD INCLUDE NINTEDANIB AS OUR STUDY RESULTS.

研究设计

研究类型: Interventional
分配方式: Not Applicable
盲法: Not Applicable

入排标准

年龄范围: 18.00 Year(s) 至 80.00 Year(s)（—）
性别: All

入选标准

•All cases of covid 19 pneumonia who were diagnosed as COVID positive â‰¥15 days back or antibody positive and continue to be breathless symptomatically, have SPo2 â‰¤96%, CT-severity score â‰¥10 and CORADS-4/5/6.

排除标准

•Patients having other interstitial lung diseases.
•Patient having CKD or creatinine clearance <30 and CLD with deranged LFT will be excluded. -Not fulfilling the criteria for study -Not giving consent for study.

结局指标

主要结局

Improvement in CT-severity score

时间窗: 0, 6weeks, 12weeks

Improvement in Arterial Blood Gas.

时间窗: 0, 6weeks, 12weeks

次要结局

Improvement in 6Minute Walk Distance.(6 weeks, 12 weeks)

研究者

发起方

PRATIMA SINGH

申办方类型

Other [self]

研究点 (1)

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