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临床试验/NCT04221386
NCT04221386暂停不适用

Melodic Intonation Therapy for Tone Language Speakers

The Hong Kong Polytechnic University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2020年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
暂停
入组人数
40
试验地点
1
主要终点
Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery

研究概览

简要总结

One of the traditional therapies for restoring the ability of speech in aphasic patients is Melodic Intonation Therapy (MIT), in which everyday phrases are taught in a singing-like manner. The suggested mechanism for speech recovery is that because of the sharing of brain resources for language and music, the regions normally reserved for singing can be trained to help compensate the speech functions originally subserved by the damaged regions. However, this therapy has primarily been applied to speakers of non-tone languages, in which prosodic features carry a more important role than pitch features in conveying meanings. It remains unknown whether MIT will be equally applicable for speakers of tone languages, in which pitch features likely play a more important role. Another uncertainty concerns whether the efficacy of MIT can be extended to patients with expressive speech impairment due to dementia. This pilot study aims to find out the efficacy of MIT for speech-impaired dementia patients in different verbal tasks. The results of this study will provide preliminary empirical evidence to establish the utility of MIT for Cantonese speakers in Hong Kong.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Care Provider)

入排标准

年龄范围
50 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Early to moderate stage dementia patient
  • Normal hearing (hearing aid accepted)
  • Non-fluent speech (max. score of fluency in Cantonese Aphasia Battery spontaneous speech subtest = 6/10)

排除标准

  • Non-native Cantonese speaker
  • Illiterate
  • Aphasic patients
  • Subjects who receive other speech therapy during study

结局指标

主要结局

Change in Aphasia Quotient (AQ) in Cantonese Aphasia Battery

时间窗: within a week after procedure

Two subtests of the Cantonese Aphasia Battery (auditory comprehension \& spontaneous speech) will be executed. Higher AQ means better performance in the respective areas. The minimum of AQ in each subtest is 0, and the maximum is 20.

次要结局

  • Change in latency and accuracy in picture naming task(within a week after procedure)
  • Change in performance of semantic fluency task(within a week after procedure)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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