Evaluating Papilla Access Tunnel Technique with Platelet-Rich Fibrin and Amnion-Chorion Membrane for Management of Anterior Gingival Recessions: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Probing Pocket Depth
研究概览
简要总结
Gingival recession, also known as soft tissue recession, is defined as the displacement of
the gingival margin apical to the cemento-enamel junction (CEJ) of a tooth or the platform
of a dental implant.This condition is associated with issues like dentine
hypersensitivity, non-carious cervical lesions (NCCLs), and compromised aesthetics.
Dealing with recession defects in the anterior region presents challenges due to various
anatomical factors, including the depth of the vestibule, position of the tooth, pull of
muscles and frenulum, and thickness of hard and soft tissues.
Several surgical techniques have been proposed over the years for treating mucogingival
defects in the aesthetic zone of the dentition. The Coronally Advanced Flap (CAF) along
with Subepithelial connective tissue graft (SCTG) is considered the gold standard for the
treatment of gingival recessions . Its advantages include a perfect color/contour match
with surrounding tissue and simplicity of execution.
The tunnel technique, introduced by Allen in 1994 , has evolved and the Papilla Access
tunnel technique, introduced by Edward P. Allen in 2019, is now suggested as a more
realistic option for gingival recession treatment in the anterior region. This technique
preserves papillary integrity and provides incision-free design, allowing improved surgical
access for site preparation and graft placement with reduced risk of perforation or injury to
thinner tissues
Intrasulcular approach for preparation of the tunnel site in Papilla Access tunnel technique
is accomplished easily when treating multiple tooth sites where a few of the teeth may
present with significant amount of recession by using the access provided by an elongated
sulcus associated with the recession defect.
Regarding the use of membranes. Choukroun’s platelet-rich fibrin (PRF), a secondgeneration
platelet concentrate developed in 2001 (Choukroun et al,2001), is an autologous
leukocyte and platelet-rich fibrin biomaterial. PRF offers advantages such as simplified
and efficient preparation in a single-step centrifugation process, without the need for
anticoagulants or other gelling agents.
Recently, placental-derived tissues, known for their immune privileged composition,
antibacterial properties, and facilitation of cell migration, have gained popularity in
dentistry for guided tissue regeneration . Amnion membrane, an allogenic substitute
for subepithelial connective tissue graft, is particularly used for cost-effective root coverage
.The amnion contains stem cell reserves, growth factors, and proteins that accelerate
healing and regeneration, while the chorion is rich in collagen proteins. Based on these
biological properties, amnion and chorion membranes are theorized to be effective in
managing gingival recession and are being employed in root coverage procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients presenting with Recession Type 1 RT1 Cairos classification of gingival recession involving maxilla and mandibular anterior teeth.
- •Patients who have not undergone any previous root coverage procedures Width of attached gingiva more than or equal to 2mm Patients with normal hemogram report.
排除标准
- •Patients with compromised systemic diseases Pregnancy Patients on antibiotic therapy for the past 6 months Smokers Patients with coagulation disorders Patients with malaligned anteriors.
结局指标
主要结局
Probing Pocket Depth
时间窗: At baseline | 3 months | 6 months
Clinical attachment level
时间窗: At baseline | 3 months | 6 months
Complete root coverage
时间窗: At baseline | 3 months | 6 months
Mean root coverage
时间窗: At baseline | 3 months | 6 months
Recession depth
时间窗: At baseline | 3 months | 6 months
Width of keratinized tissue
时间窗: At baseline | 3 months | 6 months
次要结局
- Root Coverage Aesthetic Score(Patient Reported Outcome Measures)
研究者
Dr. Shruti Singh
Manipal College of Dental Sciences, Mangalore
