NCT00946829已完成不适用
Study of Hypertensive Population Under Treatment With Micardis in Real Clinical Conditions With the Goal to Control the Early Morning BP Rise
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18,299
- 试验地点
- 1
- 主要终点
- Change from baseline in mean early morning systolic blood pressure, mean early morning diastolic blood pressure, and degree of control. (6:00 to 11:59), BP < 135/85 mmHg. (HBPM: mean of morning measurements).
研究概览
简要总结
The aim of the observational study is to ascertain the degree of blood pressure control in the early-morning hours after 8 weeks of treatment with Telmisartan/Telmisartan+Hydrochlorothiazide and during 44 weeks of follow-up, in patients with hypertension using home blood pressure measurements.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with mild to moderate essential hypertension and whose medical condition make them eligible for treatment with Telmisartan/Telmisartan+HCTZ
排除标准
- •Pre-menopausal women who had had no birth control, who are pregnant or nursing
- •Patients with advanced hepatic impairment, advanced renal impairment or both
- •Patients with functional class III or IV (NYHA) congestive heart failure (CHF), unstable angina, acute myocardial infarction, heart surgery or stroke within the previous six months
- •Patients with any valvular disease with hemodynamic repercussion
- •Patients receiving chronic administration of oral anticoagulants or digoxin
- •Patients with known hypersensitivity to any component in the formulation of Micardis / MicardisPlus
- •Patients with previous history of angioedema associated with ACE inhibitors
- •Patients with severe, uncontrolled hypertension or any form of secondary hypertension
- •Patients with any other clinical conditions which, in the opinion of the investigator, would not allow for the safe completion of the protocol
结局指标
主要结局
Change from baseline in mean early morning systolic blood pressure, mean early morning diastolic blood pressure, and degree of control. (6:00 to 11:59), BP < 135/85 mmHg. (HBPM: mean of morning measurements).
时间窗: 217 Weeks
次要结局
- Clinical control (office BP), response rates, reduction in office cuff systolic and diastolic BP. Office BP control criteria: BP < 140/90 mmHg. Pulse rate, pulse pressure, discontinuations and tolerability.(217 Weeks)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Blood Pressure Control and Compliance to Treatment in Hypertensive Patients With Metabolic Syndrome: a Study Based on Home Blood Pressure Telemonitoring and Assessment of Psychological DeterminantsArterial HypertensionMetabolic SyndromeNCT01541566Italian Institute of Telemedicine254
已完成
3 期
BEtter Control of Blood Pressure in Hypertensive pAtients Monitored Using the HOTMAN® sYstemHypertensionNCT01482364Hemo Sapiens, Inc.183
已完成
不适用
A Study of a Hypertensive Population Under Treatment With Micardis® and Micardis Plus® to Control the Early Morning BP Rise (SURGE II)HypertensionNCT02242396Boehringer Ingelheim5,248
Unknown
不适用
Blood Pressure During Rate Control in Patients With Tachycardic Atrial Fibrillation at the Emergency DepartmentAtrial FibrillationNCT04005482Medical University of Vienna140
Unknown
不适用
Assessment of Blood Pressure Control and Target Organ Damage in Patients With Chronic Kidney Disease and Hypertension -IIHypertensionChronic Kidney DiseaseNCT02078115Seoul National University Hospital400