Effect of Moderate Intensity Aerobic Exercise Versus Resistance Exercise on Bone Density in Postmenopausal Diabetic Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- The bone mineral density (BMD)
研究概览
简要总结
Osteoporosis is a significant public health issue, especially among postmenopausal women with diabetes, and its prevalence is increasing. This trial aims to determine the influence of moderate intensity aerobic exercise vs resistance exercise on bone mineral density among postmenopausal diabetic women.
详细描述
has diabetes. Postmenopausal Osteoporosis (PMO) is an increasingly serious metabolic bone disease in the world, which generally develops in middle-aged and elderly women and postmenopausal women, and it is characterized by low bone mass and microstructure degradation of bone tissues. there are complex pathophysiological effects between them: T2D directly affects bone metabolism and strength. Some antidiabetic drugs affect bone metabolism, and diabetes complications are related to the risk of falls and subsequent fractures. Patients with T2D have higher trabecular and lower cortical bone density, leading to lower bone intensity. Exercise is considered a highly relevant component in the prevention and treatment of osteoporosis and fracture reduction. Exercise greatly affects bone geometry as it increases periosteal apposition through increasing osteoblast formation. In addition to influencing bone mineral density, exercise can improve muscle function to potentially decrease fall risk through improved balance and strength.
The purpose of this study was to investigate the effect of moderate-intensity aerobic exercise versus resistance exercise on bone mineral density in postmenopausal diabetic women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
Double-blind masking the patient was not be informed about the training group or the other group; they will be evaluated and trained at different places and times.
入排标准
- 年龄范围
- 50 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Fifty women postmenopausal obese women
- •(BMI) 30 -35 kg/m2
- •their age ranges from 50 to 60 years old and
- •complain of diabetic type 2 for 10 years ago.
排除标准
- •women with renal or liver disease,
- •cardiac or chest disease psychological problems,
- •cognitive problems are excluded from the study.
- •Any women who have therapeutic problems that will interfere with performing exercise or affection BMD will be excluded from this study.
研究组 & 干预措施
Group (A)
25 patients receive aerobic exercise attended the program of walking on a treadmill machine for eight weeks according to specific parameters, in addition to their usual daily calcium intake.
干预措施: aerobic exercise (Procedure)
Group (A)
25 patients receive aerobic exercise attended the program of walking on a treadmill machine for eight weeks according to specific parameters, in addition to their usual daily calcium intake.
干预措施: resistance exercise (Procedure)
Group (B)
25 patients receive resisted exercise in addition to their usual daily calcium intake for 12 weeks.
干预措施: aerobic exercise (Procedure)
Group (B)
25 patients receive resisted exercise in addition to their usual daily calcium intake for 12 weeks.
干预措施: resistance exercise (Procedure)
结局指标
主要结局
The bone mineral density (BMD)
时间窗: 3 months
• Dual Energy X-ray Absorptiometry (DEXA). It was used to measure the bone mineral density (BMD) of the lumbar spine for each woman in both groups before and after the study.
次要结局
未报告次要终点