Differentiating the effects of whey protein and guar gum on postprandial glycaemia in type 2 diabetes.

Central Adelaide Local Health Network0 个研究点目标入组 22 人开始时间: 2015年11月23日最近更新: 2020年1月13日

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•Male or female patients with a diagnosis of type 2 diabetes by WHO criteria (plasma glucose equal to 7.0 mmol/L fasting, or greater than 11.1 mmol/L two hours after a glucose challenge) or with a history of HbA1c greater than or equal to 6.5%, managed by diet or metformin
•* Age 18 – 75 years
•*Body mass index (BMI) 20- 40 kg/m2, and weight-stable
•*HbA1c greater than equal 6.0% and less than or equal to 7.9% at the time of screening
•*Haemoglobin above the lower limit of the normal range (i.e. greater than 135 g/L for men and 115 g/L for women), and ferritin above the lower limit of normal (i.e. greater than 10 mcg/L)

•*Requirement for antidiabetic medications other than metformin
•*Significant gastrointestinal symptoms, or history of gastrointestinal disease including known gastroparesis, or surgery (other than appendicectomy or cholecystectomy)
•*Intake of greater than 20 g alcohol on a daily basis, or cigarette smoking
•*Volunteers who have donated blood in the preceding 3 months
•*Current use of medications which are likely to affect gastrointestinal function or appetite (opiates, anticholinergics, levodopa, beta blockers, clonidine, nitrates, tricyclic antidepressants, selective serotonin re-uptake inhibitors, phosphodiesterase type 5 inhibitors, sumatriptan, metoclopramide, domperidone, cisapride, tegaserod, or erythromycin)
•*Females of childbearing age who are pregnant, or lactating , or have inadequate contraception
•*Vegetarians

发起方

Central Adelaide Local Health Network