The Effects of a Cognitively-based Compassion Training on Health and Social Interaction in Depressed Patients and Their Partners
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- Eye gaze patterns
研究概览
简要总结
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners. compare healthy and depressed couples during an instructed positive real-time social interaction in the laboratory.
Furthermore the investigators aim to examine how social behavior and psychobiological indicators of health during real-time social interaction in the laboratory might be improved through CBCT® for couples.
详细描述
Objects:
Will a CBCT® (Cognitively Based Compassion-Training) for couples reduce the depressive symptomatic and the partners´ burden as well as improve behavioral, endocrine, physiological and immune responses during a real time social interaction in the laboratory.
Do couples with a depressed female partner differ from healthy control couples in behavioral, endocrine, physiological and immune responses during a instructed positive real-time social interaction in a laboratory setting?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •General inclusion criteria:
- •being in a heterosexual relationship for two years or more
- •agreement to participate in the study
- •recurrent depression (ICD-10 F33.0 or F33.1, depressed females of the patient couples only)
- •agreement of the patient couples to be randomized into the two treatment arms
- •no mental disorders (healthy control group only)
排除标准
- •severe acute and chronic psychological ( suicidal tendency, acute affective bipolar disorders) or physical disorder (chronic diseases, severe diseases such as endocrinological, neurological, nephrological or hepatic disorders)
- •being pregnant
- •heavy smoking (more than 20 cigarettes daily) or alcohol abuse
- •substance related abuse and addiction
- •enrolling current couple therapy
- •enrolling current individual therapy (except of probatory phase)
- •enrolling current mindfulness or compassion based group training
研究组 & 干预措施
CBCT® for Couples
The CBCT® (Cognitively Based Compassion-Training) for couples (CBCT®-fC) consists of a ten-week training program with a 2h group session weekly and daily home practice based on prerecorded guided mediations (Emory University, Atlanta, USA; Ozawa-de Silva & Negi, 2013). The ten weeks start with an overview and a take-home ideas for continuing practice. Furthermore the first and the 3rd module will be repeated once resulting in a total of ten weeks. Further couple- and dyadic exercises are added.
It focuses on six essential key parts for the development of compassion:
- Developing attentional stability and clarity of the mind (Mindfulness)
- Cultivating insight into the nature of mental experience
- Cultivating self-compassion
- Developing impartiality
- Developing appreciation and affection for others
- Developing empathy and realizing engaged compassion
干预措施: CBCT® (Cognitively Based Compassion-Training) (Behavioral)
Treatment as usual (TAU)
Treatment as usual: Primary care according to guidelines from the S3- and national healthcare guideline "Unipolar Depression" [S3-Leitlinie und Nationale VersorgungsLeitlinie (NVL) Unipolare Depression, Ärztliches Zentrum für Qualität in der Medizin], but excluding current psychotherapy after probatory session.
结局指标
主要结局
Eye gaze patterns
时间窗: 4 weeks after recruitment and 12 weeks after first test
Changes in eye gaze patterns (total fixation time \& fixation count) as behavioural component measured during standardised positive social interaction- pre \& post training.
Circadian variation pattern of heart rate variability
时间窗: 4 weeks after recruitment and 12 weeks after first test
Changes in circadian variation pattern of heart rate variability pre \& post training.
Depressive symptoms
时间窗: 4 weeks after recruitment and 12 weeks after first test
Change in depression score (observer rating Hamilton Depression Rating Scale \[HDRS\], self-rating Becks Depression Inventory \[BDI\]) after CBCT® (Cognitively Based Compassion Training) for couples in comparison to control TAU-group (treatment as usual).
次要结局
- Analysis of psychometrical self- and observer rating und their correlations(4 weeks after recruitment and 12 weeks after first test)
- Biopsychological concomitants of depressive disorders(4 weeks after recruitment and 12 weeks after first test)
研究者
Beate Ditzen
Prof. Dr. phil. Dipl.- Psych. Beate Ditzen
Heidelberg University