ISRCTN31129526已完成不适用
Effect of Angiotensin Converting Enzyme Inhibition (ACEI) on C-Reactive Protein (CRP) Levels: The Ramipril CRP Randomized Evaluation (4R Trial)
Sanofi-Aventis (Canada)0 个研究点目标入组 400 人开始时间: 2006年1月6日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •35-80 years of age, male or female, free of cardiovascular disease, and baseline CRP greater than 2 mg/l
排除标准
- •1. Structural heart disease or vascular disease
- •2. Systolic blood pressure greater than 160 or less than 100 mmHg
- •3. Renal or hepatic dysfunction
- •4. White blood cell (WBC) count greater than 12,000
- •5. Chronic inflammatory disease
- •6. Human Immunodeficiency Virus (HIV)
- •7. Known sensitivity to ACEI
- •8. Steroid use
- •9. Chronic (more than 2 weeks) use of non-steroidal anti-inflammatory drugs (NSAIDs)
- •10. Treatment with:
- •a. ACEI or Angiotensin II Receptor Blockers (ARB)
- •b. Lipid lowering agents
- •c. Hormone replacement therapy
- •d. Oral hypoglycemic agents
- •f. Antioxidants
- •11. Failure to give informed consent
研究者
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