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临床试验/TCTR20240409004
TCTR20240409004尚未招募不适用

The Venous Excess Ultrasound (VExUS) grading to predict tolerance to fluid de-escalation in critically ill patients

Faculty of Medicine Ramathibodi Hospital, Mahidol University0 个研究点目标入组 65 人开始时间: 2024年4月9日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
65

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 100 Years(—)
性别
All

入选标准

  • 1.Adult patients (age 18 years and over) admitted in intensive care units (both medical and surgical ICU) of Ramathibodi Hospital
  • 2.Presence of fluid accumulation, defined as positive fluid balance 10% or more of body weight
  • 3.Hemodynamic stability, defined as
  • a. Adequate tissue perfusion (capillary refilling time less than 3 seconds)
  • b. Mean arterial pressure more than 65 mmHg with
  • i.Clearing decreasing dose of vasopressor
  • ii.Norepinephrine less than 0.2 mcg/kg/min
  • iii.Arterial lactate level less than 2 mmol/L
  • 4.Need for fluid de-escalation, as decided by the attending physicians

排除标准

  • 1.Patients who refused to participate in the study or withdraw from the study
  • 2.Patients who had severe chronic kidney disease (estimated glomerular filtration rate less than 15 mL/min per 1.73 m2 or in regular dialysis program) or renal transplantation
  • 3.Patients with obstacles to abdominal ultrasound include severe obesity (BMI of 40 or higher), having had abdominal surgery or having abdominal burn wounds in the positions that may impede ultrasound.
  • 4.Patients with previously known conditions that interfere with portal Doppler assessments (liver cirrhosis, portal vein thrombosis, or severe tricuspid regurgitation with structural heart disease)
  • 5.Pregnancy

研究者

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