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临床试验/NCT05354154
NCT05354154Unknown不适用

Incidence of Postoperative Sore Throat and Risks Analysis in Patients Undergoing General Anesthesia With Endotracheal Intubation: A Prospective Cross-sectional Study

Rehman Medical Institute - RMI1 个研究点 分布在 1 个国家目标入组 249 人开始时间: 2022年4月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
249
试验地点
1
主要终点
Incidence rate of sorethroat

研究概览

简要总结

Postoperative sore throat is a distressing but frequent symptom presented by the patients on the floor upon awakening from General Anesthesia, where endotracheal intubation is part of the Anesthetic protocol. Its incidence ranges between 21-71.8%. Good skills and availability of trained staff to cause minimal tissue damage are expected to reduce the incidence. Risks factors associated will be analyzed.

详细描述

Post-operative sore throat (POST) is a common complication of endotracheal intubation. It ranges from 21 to 71.8 %. Various factors contribute to the development of POST, like, female sex, smoking, intubation difficulty and Suxamethonium use, high endotracheal cuff pressure, airway suctioning, long duration of surgery, mucosal injury with laryngoscopy, or pharyngeal airway use and larger size endotracheal tubes [9]. POST has also been associated with laryngeal masks, injury with laryngoscopy, or pharyngeal airway use and larger size endotracheal tubes. Basically it is mucosal damage of the throat and trachea which releases inflammatory mediators and produces soreness. POST leads to postoperative dissatisfaction. Patients of POST are uncontended following general anesthesia. Its preemptive amelioration, has been studied using various pharmacological interventions. The list includes, but is not limited to, Benzydamine hydrochloride (BH), aspirin, ketamine, lidocaine and dexamethasone. There is limited evidence based literature available about the incidence of POST in the investigator's locality in the country. The investigators plan to collect data in General OT of Rehman Medical institute (RMI), Peshawar. The city of Peshawar is the largest city of Khyber Pakhtunkhwa, a province of Pakistan, having a population of approximately 2 million. The objectives of our study is to know the magnitude of the problem and ascertain factors associated with postoperative sore throat among patients undergoing elective surgery under general anesthesia with endotracheal intubation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Any patient of either gender aged 18- 60 years
  • Patients of American Society of Anesthesiologists (ASA) physical status 1 and 2 receiving General Anesthesia with ETT

排除标准

  • Patients having ASA 3 or above physical status
  • Recent or ongoing Upper Respiratory Tract Infection (URTI)
  • Patients going to ICU intubated

结局指标

主要结局

Incidence rate of sorethroat

时间窗: Six hours

Incidence= Those who developed Postoperative sorethroat / All recruited participants who recieve General anesthesia through endotracheal tubes \*100

次要结局

  • Risk factors assessment(Six hours)

研究者

发起方
Rehman Medical Institute - RMI
申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohammad Shafiq

Principal investigator

Rehman Medical Institute - RMI

研究点 (1)

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