An Open Labelled Randomized Standard Controlled Clinical Study On Efficacy Of Saptamruta Lauha In Vitamin B12 Deficiency (Pandu)
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Saptamruta lauha is effective in improving serum vitamin B12 level in patients of vitamin B12 deficiency
研究概览
简要总结
Vitamin B12 is a essential vitamin, It plays a critical role in various physiological function, including red blood cell formation, neurological function, and DNA synthesis.
Vitamin B12 also known as cobalamin, is a vital water-soluble vitamin, plays vital role in maintenance of proper neurological function through its involvement in myelin production and nerve cell metabolism. Beyond these primary roles, vitamin B12 also contributes to energy production and supports cardiovascular health by regulating homocysteine levels.
The aetiology of vitamin B12 deficiency is multifactorial, It can result from dietary insufficiency, maldigestion, malabsorption syndrome, genetic mutations impacting transport proteins like transcobalamin. “Intrinsic factor”, A glycoprotein secreted by the stomach’s parietal cells, Thus any disruption in its production or function may lead to deficiency.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Serum Vitamin B12 level below 300 Pg/DL.
排除标准
- •1.Patient suffering from any other severe cardiac disease, advanced liver and kidney diseases, malignancies 2.pregnant women, lactating women 3.Patients taking proton pump inhibitors, h2 blocker, metformin Recent vitamin B12 supplementation within the past 3 months.
结局指标
主要结局
Saptamruta lauha is effective in improving serum vitamin B12 level in patients of vitamin B12 deficiency
时间窗: 30 Days
次要结局
- Sapatamruta Lauha is effective in improving symptoms of Vitamin B12 deficiency(30 Days)
研究者
Dr Haritkumar Sojitra
G.J Patel Institute Of Ayurvedic Studies And Research