Long Term Outcome Study in Patients With Pituitary Disorders
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,500
- 主要终点
- Progression free survival after pituitary surgery
研究概览
简要总结
To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.
详细描述
A chart audit of around 1500 patients seen in two specific clinics, the Medical Pituitary Clinic and the combined Endocrine/Neurosurgical Pituitary Clinic at the University of Alberta Hospital, will be performed to determine the effectiveness of various treatment strategies on the long term outcome of specific pituitary disorders. The investigator's will collect retrospective demographic (age, sex, ethnicity), clinical (mode of presentation, hormonal parameters) and therapeutic outcome (surgical, medical, expectant and / or radiation treatment; co-morbidities and complications) of patients seen in these two clinics between January 2000 and December 2020.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with confirmed pituitary disease
排除标准
- •patients who do not have confirmed pituitary disease
结局指标
主要结局
Progression free survival after pituitary surgery
时间窗: up to 17 years post surgery
Using clinical, biochemical and imaging studies of a cohort of surgically operated patients to identify prognostic factors of tumor recurrence
次要结局
未报告次要终点