Comparing efficacy of three strategies for weaning of High Flow Nasal Cannula in critically ill patients with Acute Hypoxemic Respiratory Failure: Exploratory Randomized Trial - NI

AIIMS Rishikesh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年3月4日

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•The patients on HFNC for AHRF and satisfying all of the following weaning criteria:
•1. Age more than 18 years
•2. No signs of respiratory distress (increased work of breathing, use of accessory muscles of respiration leading to diaphoresis, anxiety or agitation)
•3. Arterial pH more than or equal to 7.35, SpO2 more than 90% on FiO2 less than or equal to 0.6
•4. Respiratory rate less than 25/min, Heart rate less than 120/min, Systolic blood pressure more than or equal to 90 mmHg.

•1. Respiratory failure requiring or receiving endotracheal intubation or IMV during the current hospital stay.
•2. Cardiac arrest, Acute Coronary Syndrome or life-threatening arrhythmias
•3. More than or equal to 2 end organ failure other than respiratory failure defined as acute change in total SOFA score more than or equal to 2 points.
•4. Patients with recent trauma or burns to the neck and face
•5. Hypercapneic respiratory failure (pH less than 7.35 and PaCO2 more than 45)

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