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临床试验/NCT06409234
NCT06409234尚未招募不适用

EuPreCHO: European Study on Perioperative Management and Outcome Following Preoperative Transthoracic Echocardiography in Noncardiac Surgery Patients

European Society of Anaesthesiology1 个研究点 分布在 1 个国家目标入组 8,250 人开始时间: 2024年6月30日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
8,250
试验地点
1
主要终点
Major Pathology

研究概览

简要总结

In August 2022 the European Society of Cardiology published updated guidelines including recommendations on preoperative transthoracic echocardiography. The update resulted in broadened criteria for preoperative transthoracic echocardiography. The impact of preoperative transthoracic echocardiography on outcome is controversial and the evidence was mostly derived from administrative databases. Also there is also a knowledge gap in terms of what changes in perioperative managements are derived from transthoracic echocardiography information in current daily practice in Europe and what their impact on outcome may be. Further, a secondary analysis in a large international cohort suggests that the criteria endorsed by the guidelines to define the class of recommendation of transthoracic echocardiography may not be efficient.

详细描述

The target population consists of patients at elevated cardiovascular risk undergoing elective, intermediate or high-risk noncardiac surgery. The planned sample size is 5500 exposed and 2750 non-exposed

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Major Pathology

时间窗: 30 days

Decreased contractility (LVEF ≤40% by Simpson's method or eyeballing) or based on corresponding qualitative statement in TTE report. Significant LV diastoic: E/A \<0.8 + E\>50cm/sec OR E/A \>0.8 to \<2 + at least ≥ 2 additional criteria ( Average E/e' ratio \>14, peak TR velocity \>2,8 m/sec, LA volume index \>34 mL/m2.

次要结局

  • Disability-free survival at 30 days(30 days)

研究者

发起方
European Society of Anaesthesiology
申办方类型
Other
责任方
Sponsor

研究点 (1)

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