HPV Infection and Cervical Neoplasm in Women With Inflammatory Bowel Disease: a Cross-sectional Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- The different incidence of cervical neoplasm between controls and patients by performing Thinprep Cytology Test
研究概览
简要总结
The associations between female inflammatory bowel disease (IBD) patients and human papilloma virus (HPV) infection and cervical neoplasia (dysplasia or cancer) were unclear. Especially there was no data for Chinese IBD population. So we investigated the incidence and risk factors of HPV infection and cervical neoplasia (dysplasia or cancer) in female IBD patient.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •between 20-60 years old;
- •Patients diagnosed as IBD according to previously established international criteria
排除标准
- •Patients refuse to participating
结局指标
主要结局
The different incidence of cervical neoplasm between controls and patients by performing Thinprep Cytology Test
时间窗: July 2015 to July 2017
The difference of the incidence of cervical neoplasm between healthy control and IBD patients was not clear.All the controls and patients are going to perform Thinprep Cytology Test which could detect intraepithelial neoplasia of cervix.
The different infection rate of HPV between controls and patients by detecting HPV-DNA using reverse dot-blot method.
时间窗: July 2015 to July 2017
The difference of infection rate of HPV between healthy control and IBD patients was not clear.We are detecting HPV-DNA by reverse dot-blot and calculate the positive rate of HPV infection among controls and patients.
次要结局
- Find drugs relating to HPV infection of IBD patients(July 2015 to July 2017)
研究者
Xiang Gao
Professor
Sixth Affiliated Hospital, Sun Yat-sen University