Impact of HPV on a Cohort of Southern Italian Women: Epidemiological, Clinical, Morphological and Microbiological Features
Not Applicable
Completed
- Conditions
- Cervix Cancer
- Registration Number
- NCT03959410
- Lead Sponsor
- University of Campania "Luigi Vanvitelli"
- Brief Summary
HPV is known to be the causal agent in the majority of cervical cancers. However, the role of the cervical bacterial microbiome in cervical cancer is not clear
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
- Women in fertile age
Exclusion Criteria
- severe comorbidities
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Evaluation of Cervical microbiome 12 months
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link HPV infection to cervical cancer progression in Southern Italian populations?
How does the cervical bacterial microbiome interact with HPV in influencing cervical cancer risk and outcomes?
Are there specific HPV genotypes associated with distinct clinical or morphological features in cervical cancer cases from Southern Italy?
What biomarkers can predict response to cervical biopsy-based diagnostic approaches in HPV-related cervical cancer?
How does the efficacy of cervical biopsy compare to other diagnostic methods in detecting HPV-induced precancerous lesions in Southern Italy?
Trial Locations
- Locations (1)
Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli"
🇮🇹Napoli, Italy
Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli"🇮🇹Napoli, Italy