Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Central macular thickness
研究概览
简要总结
The purpose of this study is to determine whether intraocular injection of triamcinolone is effective in the treatment of macular edema in acute branch retinal vein occlusion.
详细描述
Intravitreal triamcinolone has recently been shown to have beneficial effect on chronic macular edema due to vein occlusion and preventive effect on neovascularization. Hypothetically, prevention of macular derangement by reducing the amount of edema from early phase after occlusion until restoration of collaterals seems to be helpful in these eyes. To our knowledge, no prospective randomized clinical trial, considering both macular changes and preventive effect on neovascularization has been published for intravitreal triamcinolone in acute branch retinal vein occlusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Eyes suffering from branch retinal vein occlusion with less than 2 months duration.
排除标准
- •Monocularity,
- •Previous intraocular surgery or laser therapy
- •Glaucoma or ocular hypertension
- •Significant media opacity
- •Existence of traction on the macula
- •Visual acuity ≥20/40
- •Signs of chronicity (such as cilioretinal and/or retinal shunt vessels)
结局指标
主要结局
Central macular thickness
次要结局
- Visual acuity
- Retinal neovascularization
- Intraocular pressure
- Cataract progression