NCT04154540已完成不适用
Study of Gait and Posture in Subacute Acquired Neuropathies and in Hereditary Neuropathies
University Hospital, Lille1 个研究点 分布在 1 个国家目标入组 67 人开始时间: 2021年5月19日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 67
- 试验地点
- 1
- 主要终点
- Posturography (Romberg's quotient)
研究概览
简要总结
If the classification between hereditary and acquired neuropathy is often easy, there is no completely specific marker allowing the distinction between the two etiologies. Clinical experience suggests that hereditary neuropathies have less impact on balance and gait than the acquired neuropathies at equivalent level of impairment, but this has never been clearly demonstrated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CMT1A for molecular-proven Group 1 (PMP22 duplication)
- •IPDC likely or defined for Group 2
- •Able to walk 10 m unassisted
排除标准
- •Neurological history other than neuropathy: epilepsy, stroke, dementia
- •Pregnant women
- •Person under guardianship or trusteeship
- •Musculoskeletal conditions other than neuropathy impairing walking abilities
- •Major comorbidity considered a contraindication by the investigator (cancer, unstable angor, etc.)
研究组 & 干预措施
demyelinating hereditary neuropathy
Experimental
adult patients with demyelinating hereditary neuropathy type CMT 1A.
干预措施: Motion analysis (Other)
demyelinating inflammatory neuropathy
Experimental
adult patients with acquired demyelinating inflammatory neuropathy.
干预措施: Motion analysis (Other)
结局指标
主要结局
Posturography (Romberg's quotient)
时间窗: Time 0 ; single session
次要结局
- stride time (in seconde) parameters(Time 0 ; single session)
- velocity (meter/seconde) parameters(Time 0 ; single session)
- cadence (step/min) parameters(Time 0 ; single session)
- The Timed Up and Go test (TUG)(Time 0 ; single session)
- stride length (in millimeters) parameters(Time 0 ; single session)
研究者
研究点 (1)
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