临床试验/NCT01710436

NCT01710436Unknown不适用

Relationship Between Dosage of Clopidogrel and Platelet Aggregation in Chinese With Different Genotype

Chinese Academy of Medical Sciences, Fuwai Hospital1 个研究点分布在 1 个国家目标入组 880 人开始时间: 2012年10月最近更新: 2013年5月20日

适应症

试验速览

阶段: 不适用
发起方
入组人数: 880
试验地点: 1
主要终点: Change from Baseline in platelet aggregation

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study is a prospective, observational study to estimate the relationship between dosage of clopidogrel and platelet aggregation in Chinese with different genotype. The investigators suppose both pretreatment dosage of clopidogrel before percutaneous coronary intervention (PCI) and CYP2C19 genotype may effect the platelet aggregation as well as clinical outcome.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•accept PCI in Chinese CHD patients
•expected dual antiplatelet therapy (DAPT) at least 6 months

排除标准

•another planned PCI within 6 months

结局指标

主要结局

Change from Baseline in platelet aggregation

时间窗: 1 month and 6 months after PCI

次要结局

Major adverse cardiovascular events (MACE); Bleeding events(6 months after PCI)

研究者

发起方

Chinese Academy of Medical Sciences, Fuwai Hospital

申办方类型

Other

责任方

Principal Investigator

主要研究者

Xiaoxing Zhang

Chinese Academy of Medical Sciences, Fuwai Hospital

研究点 (1)

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