A New Approach to Clinical Implication of Detrusor After-contraction (DAC)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,309
- 试验地点
- 1
- 主要终点
- to confirm whether DAC is a true contraction or not
研究概览
简要总结
The aims of this study are
- to confirm whether detrusor after-contraction (DAC) is a true contraction or not with a new approach
- and to understand clinical implication of DAC
详细描述
The definition of detrusor after-contraction (DAC) is usually accepted as the increase of detrusor pressure (Pdet), whether it is sudden or not, after cessation of urinary flow. The amount of increase in Pdet is sometimes included in the definition of DAC (14, 15, 20 cmH2O or at least two times the level of the maximal Pdet during the voiding phase). However, it is clear that the lack of a well-established definition may induce much bias in the interpretation of the clinical implication of DAC. The previous studies showed a wide range of prevalence.1-4 DAC seemed to occur more frequently in children and the occurrence rate usually decreased with age in urodynamic studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Indications and selection of patients for conduction of urodynamic studies (UDS) were followed as the recommendation of ICS (international continence society).
排除标准
- •Patients with indwelling catheters, urinary tract infection and urinary stones were excluded from this study
结局指标
主要结局
to confirm whether DAC is a true contraction or not
时间窗: up to 2 years (2007.Jan-2008.Dec)
no change of Pdet when patients cough could confirm that DAC was a true contraction. Because an artifact occurred when a catheter was pressed against bladder wall or urethra, no change of intravesical pressure and increase of abdominal pressure finally induced a negative deflection of Pdet and this change of Pdet could be regarded as an artifact.
次要结局
- Past medical history including neurological disorders and pelvic irradiation were also included in the database(up to 2 years (2007.Jan-2008.Dec))