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临床试验/TCTR20230317005
TCTR20230317005已完成3 期

Comparison of amino acid loss during hemodialysis between amino acid plus dextrose infusion and sequential dextrose and amino acid infusion: a randomized, crossover trial

Phramongkutklao Hospital0 个研究点目标入组 10 人开始时间: 2023年3月17日最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
入组人数
10

研究概览

简要总结

The mean plasma amino acid concentration change was -3,211.45 (-6,485.29, 1,487.38) mcg/L and -3,630.36 (-5,253.38, -2,104.91) mcg/L in a sequential and continuous regimen, respectively. The constant infusion had much more total amino acid in dialysate by 2,587.33 (81.18, 5,093.48) mcg/L. Sequential infusions had hypotension of 20% and higher capillary glucose levels at the second hour of dialysis.

研究设计

研究类型
Interventional

入排标准

年龄范围
N/A (No limit) 至 1 Years(—)
性别
All

入选标准

  • •Age more than 20 years
  • •Chronic hemodialysis on 3per week
  • •Informed consent
  • •Indication for IDPN according to Clinical practice recommendation for Nutrition Management in Adult Kidney Patients 2018

排除标准

  • •Volume overload
  • •Hypotension from cardiac cause
  • •Advanced malignancy
  • •Advanced liver disease
  • •Blood flow rate < 250 ml/min

研究者

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