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临床试验/NCT07143721
NCT07143721进行中(未招募)不适用

Comparison of the Effect of Different Inspiratory Loads on Diaphragmatic Function in Healthy Individuals

University of Vigo1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2025年6月30日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
10
试验地点
1
主要终点
Change in diaphragmatic excursion during inspiratory muscle training at varying loads

研究概览

简要总结

This pilot study aims to evaluate how the diaphragm responds to different inspiratory muscle training loads using ultrasound in healthy individuals. The observational, cross-sectional research seeks to determine whether ultrasound measurements of diaphragm movement and thickness can more effectively guide load prescription, thereby optimizing the benefits of inspiratory training. Twenty healthy participants, of both sexes, aged 18 to 35 years, will be recruited through outreach at the Faculty of Physiotherapy at the University of Vigo. The assessment will include spirometry, maximum inspiratory pressure (MIP) measurement, and ultrasound evaluations of the diaphragm at various loads (10%, 30%, 50%, and 70% of the MIP). Data will be analyzed to understand how diaphragm mobility, thickness, and contraction velocity vary according to load, with the goal of improving training prescription and adjustment. The study adheres to the ethical principles of the Declaration of Helsinki and ensures strict confidentiality and participant anonymity. The results will contribute to the understanding of non-invasive diaphragm assessment and its role in enhancing respiratory and physical performance.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Healthy adults aged 18 to 35 years
  • •No history of neuromuscular, cardiovascular, respiratory, or musculoskeletal diseases that could limit participation
  • •Not currently on medication affecting muscle function
  • •Willing to provide informed consent

排除标准

  • •Pregnant women
  • •Recent thoracic or abdominal trauma (within the last 3 months)
  • •Respiratory symptoms in the last two weeks
  • •Conditions preventing performing forced inspiratory maneuvers
  • •Recent respiratory muscle training (within the last 6 months)

结局指标

主要结局

Change in diaphragmatic excursion during inspiratory muscle training at varying loads

时间窗: Day 2: Baseline; Immediately after 10% MIP; Immediately after 30% MIP; Immediately after 50% MIP; Immediately after 70% MIP

Assessment of diaphragmatic excursion using ultrasound at 10%, 30%, 50%, and 70% of maximum inspiratory pressure (MIP). Evaluates the diaphragm's mobility as a primary measure of functional response to different inspiratory loads in healthy individuals.

次要结局

  • Diaphragmatic thickness at different inspiratory loads(Day 2: Baseline; Immediately after 10% MIP; Immediately after 30% MIP; Immediately after 50% MIP; Immediately after 70% MIP)
  • Diaphragmatic contraction velocity at different inspiratory loads(Day 2: Baseline; Immediately after 10% MIP; Immediately after 30% MIP; Immediately after 50% MIP; Immediately after 70% MIP)

研究者

发起方
University of Vigo
申办方类型
Other
责任方
Principal Investigator
主要研究者

Eva María Lantarón Caeiro

principal investigator

University of Vigo

研究点 (1)

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