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临床试验/NCT06420791
NCT06420791已完成不适用

The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma:a Two-center Retrospective Cohort Study in China

Xiao Xu1 个研究点 分布在 1 个国家目标入组 1 人开始时间: 2024年2月28日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
1
试验地点
1
主要终点
The overall survival rate was evaluated by follow-up investigation and outpatient review

研究概览

简要总结

Background: This study aims to investigate the correlation between cirrhosis and hepatocellular carcinoma (HCC) recurrence after Liver Transplantation.

Methods: The study retrospectively collected data enrolled from 519 HCC patients who underwent liver transplantation from two center(the First Affiliated Hospital, Zhejiang University School of Medicine and Shulan (Hangzhou) Hospital, January 2015 to December 2020), Based on important variables, 1:3 propensity score matching (PSM) were performed respectively.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • The patients undergoing liver transplantation for HCC from January 2015 to December 2020.

排除标准

  • Re-transplantation or combined liver-kidney transplantation; incomplete laboratory or clinical data; death within 90 days.

结局指标

主要结局

The overall survival rate was evaluated by follow-up investigation and outpatient review

时间窗: 2-5 years

次要结局

  • The tumor-free survival rate was evaluated by follow-up investigation and outpatient review(2-5 years)

研究者

发起方
Xiao Xu
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Xiao Xu

Principal Investigator, Clinical Professor,PHD,MD

Zhejiang University

研究点 (1)

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