Contributions of dorsal and ventral neural pathways to speaking in health and disease - LAPA (Language & Progressive Aphasia)

Radboud Universitair Medisch Centrum0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

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•* Inability to speak/understand the Dutch language.
•* Current psychiatric disorder, such as psychosis or major depression
•* Current substance abuse
•* Current or past neurological disorder, such as severe cerebral disease, e.g. Parkinson*s disease, epilepsy, traumatic brain injury, central nervous system infection, brain tumor, and alcoholic encephalopathy. N.B. Transient Ischaemic Attack, lacunar infarction and white matter lesions are no exclusion criteria.
•* Cognitive disorders in multiple other cognitive domains than language (e.g. memory or executive function deficits, as defined by cognitive test performance 2 or more standard deviation below normative scores);The exclusion criteria for undergoing an DTI scanning procedure are:
•* Electronically, magnetically and mechanically activated implants (e.g. cardiac
•pacemakers, defibrillators) or metallic devices (e.g. prosthetic heart valves) which
•could be affected by the magnetic field
•* Claustrophobia
•* Loose metallic objects in the body (e.g. metallic fragments in the eyes from
•occupational exposure) which could be moved by the magnetic field
•* inability to lie flat comfortably in the MRI scanner for 30 minutes

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