Efficacy of Individualized Homoeopathic Medicines in Treatment of Moderate Depression: A Double-blind, Randomized, Placebo-controlled Clinical Trial

ational Institute of Homoeopathy Ministry of AYUSH Govt of India0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Cases suffering from depression, diagnosed as per DSM-V criteria [18]
•2. Moderate cases of depression (HRDS scores 14 to 18)
•3. Patients must not have been taking antidepressants or anxiolytic drugs at the time of inclusion
•4. Both male and female patients
•5. Age between 18 and 65 years
•6. Capability and willingness to give informed consent and to comply with the study procedures
•7. Literate patients who can read English and/or Bengali

•1. Mild (HRDS 13 or less) cases of depression
•2. Severe or very severe depression (HRDS more than 19); with or without suicide attempt
•3. Spontaneous improvement by 25% or more in HDRS during the 1-week placebo run-in prior trial enrolment
•4. Patients with other psychiatric diseases; e.g. schizophrenia or other psychotic disorders, bipolar affective disorder, schizoaffective disorders, alcohol or other substance abuse, eating disorders, psychosis, mania, hypomania or any other Axis I disorder except panic disorder, personality disorders, history of seizures
•5. A clinically significant acute or chronic disease that would hinder regular participation in the study
•6. Treatment with antipsychotics, antidepressants, sedatives/hypnotics or mood stabilizers four weeks prior to the screening
•7. Complementary or alternative treatment used simultaneously to the study (for example acupuncture, phytotherapy, psychotherapy etc.)
•8. Homeopathic treatment for any chronic diseases eight weeks prior to study entry
•9. Cases suffering from uncontrolled systemic illness or life-threatening infections
•10. Self-reported immune-compromised state
•11. Pregnant women and lactating mothers

发起方

ational Institute of Homoeopathy Ministry of AYUSH Govt of India