Effect of Prolonged Sitting on Metabolic and Cardiovascular Responses to Short-Term Exercise Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Plasma Triglycerides
研究概览
简要总结
Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 to 35 years
排除标准
- •cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
- •respiratory problems
- •musculoskeletal problems that prevent prolonged sitting or exercise
- •susceptibility to fainting
- •pregnancy
研究组 & 干预措施
Sitting with Exercise
Subjects will complete a short term training protocol while sitting >11 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training.
干预措施: Prolonged sitting with exercise (Behavioral)
Walking with exercise
Subjects will complete a short term training protocol while sitting <5 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training.
干预措施: Active walking with exercise. (Behavioral)
结局指标
主要结局
Plasma Triglycerides
时间窗: 6 hours
Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test
次要结局
- Plasma Insulin(6 hours)
- Plasma glucose(6 hours)
研究者
Edward F. Coyle
Professor
University of Texas at Austin