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临床试验/JPRN-UMIN000013418
JPRN-UMIN000013418已完成未知

Pharmacokinetics and pharmacodynimics of intravenous acetaminophen in Japanese surgical patients - Pharmacology of intravenous acetaminophen

Anesthesiology, Fukushima Medical University0 个研究点目标入组 60 人开始时间: 2014年3月14日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
60

研究概览

简要总结

sing 185 datapoints from 12 patients, the pharmacokinetics of i.v. acetaminophen were described by a two compartment model with weight as a covariate. The pharmacokinetic model of i.v. acetaminophen reported by Wurthwein et al.(Eur J Clin Pharmacol.2005;60:883) worked well. Above pharmacokinetic analysis was published as a final result. (J Anesth, DOI 10.1007/s00540_017_2358_7)

研究设计

研究类型
Interventional

入排标准

年龄范围
18years-old 至 75years-old(—)
性别
All

入选标准

  • 未提供

排除标准

  • 1.Known allergy to acetaminophen 2.Psychoneurotic disorders 3.Psychiatric pharmacotherapy 4.Chronic use of ACET, NSAIDs or opioids 5.Women who were pregnant or breast-feeding 6.Anemia 7.Liver or advanced renal dysfunction 8.Those who were considered inadequate

研究者

发起方
Anesthesiology, Fukushima Medical University

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