A comparative clinical study to evaluate the efficacy of Varun Twak Lepa with Aja Dugdha and Go Dugdha in the management of Vyanga wsr melasma
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Changes in MASI scale .
研究概览
简要总结
Today, the whole world is looking towards Ayurveda with great expectations; they have realized the significance of Ayurveda. People search for the Ayurveda as it maintains longevity, beautification and minimal adverse effects of the drugs. The prime objective of Ayurveda is to maintain and reestablish the equilibrium of body tissue that is why our sages have described Trisutra1 not only for all healthy person but also for ailing.
Beauty is one of the most valued aspects in this competitive era. There is nothing like healthy skin to make an individual feel confident and beautiful, so it is no surprise that uneven skin tone can make any women and man feel self-conscious. Uneven skin tone is always frustrating factor for youth.
Acharya Sushruta and Acharya Vagbhatta has mentioned Vyanga as Kshudra Roga. All most all Acharyas have considered Vyanga as a Kshudra Roag except,Acharya Charakahas mentioned vyanga under raktadhatugata2vikara.
According to Ayurveda concepts,it is manifested due to vitiation of vata and pitta dosha. These doshas vitiated by krodha,aayas,ushna, tikshna,ruksha dietary habits. Thereby, it results in presence of niruja,tanu and shyava varan yukta mandala on mukha pradesh3.
Need of Study: -
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Vyanga (Melasma) is a condition which affects the beauty as well as personality. Now a days Vyanga has become one of the biggest problems specially in women due to excessive use of cosmetic supplements and changes occurring during pregnancy.
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There is a need to explore natural alternative as per Ayurveda classics for safe management of vyanga which is also easily available and cost effective.
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Procuring and using goat milk is a biggest challenge in today’s busy schedule and need of the hour is to fulfill this gap with maintaining characteristics of final product (lepa Kalpana)
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This gap can be fulfilled with the help of searching an alternative for the Aja dugdha in the form of Go dugdha as well as exploring options to increase the shelf life for Varun twak with Aja Dhughda lepa.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients presenting Vyanga as clinical features according to Susruta Samhita (Mandalam Visrujati, Nirujam Tanu ,Shyava).
- •Patients of either sex.
- •Patients of age between
- •60 years.
- •Patients that come under the criteria of MASI scale.
排除标准
- •Melasma due to tubercular therapy or malignant cases.
- •Diagnosed patients of Carcinoma, Burns, Herpes, Eczema, Psoriasis, Measles, Chickenpox, Leucoderma and Leprosy.
- •Person suffering from any infective or contagious skin disease or under medication with antibiotics, antifungal and steroid.
- •Patients of uncontrolled hormonal disease.
- •Patients who are reporting allergic history of trial drugs.
结局指标
主要结局
Changes in MASI scale .
时间窗: Changes in MASI scale after 4th week.
次要结局
- Changes in Ayurvedic parameters i.e. varna, akriti.(â–ª)
研究者
Manisha Kumawat
National Institute of Ayurveda, Deemed to be University