跳至主要内容
临床试验/NCT06921226
NCT06921226招募中不适用

Intra-personal and Interpersonal Psychological Processes Involved in Risk-taking and Suicidal Behaviors Among Vulnerable Adolescents and Adults

Centre Hospitalier Metropole Savoie6 个研究点 分布在 1 个国家目标入组 1,400 人开始时间: 2025年6月26日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
1,400
试验地点
6
主要终点
Suicidal ideation and behaviors

研究概览

简要总结

In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year. Even more recently, the DREES (Direction de la recherche, des études, de l'évaluation et des statistiques auprès des Ministères Sociaux) published a report on May 16, 2024, showing a sharp rise in hospitalization rates for self-inflicted acts among female patients aged between 10 and 24, with a peak around age 15. Two-thirds of these hospitalizations for self-inflicted injuries are related to deliberate drug intoxication. Depression, bipolar disorders and schizophrenia spectrum disorders (among other psychological disorders) are known risk factors for suicide, which is the leading cause of death in this clinical context. In addition to these formalized psychopathological elements, risk behaviors underpinned by psychological processes common to suicide attempts are suspected and need to be studied in depth.

Research into psychiatry and the psychopathology of suicide has identified a number of risk and protective factors. These psychological determinants - or processes - act alongside other key factors such as the environment and social ties. Life contexts can have an impact on health, and more specifically on the psychopathology of individuals, through disturbances of a biological, psychological and social nature. It is important to be able to describe what processes are at work and how they explain the development and maintenance of behaviours that put one's life and health at risk. This is part of a preventive approach to mental health. We suggest that the study of psychological processes such as suicidal ruminations, impulsivity and interpersonal needs (e.g. the interpersonal theory of suicide) is necessary to understand their involvement in risk-taking and suicidal behavior. To our knowledge, few studies of this type are underway in France, particularly with vulnerable clinical populations (adolescents/adults). The inclusion of a process-centered approach (Kinderman, 2015), in a transdiagnostic and preventive way, constitutes an innovative approach.

详细描述

The aim of this study is to describe psychological processes that contribute to risk-taking and suicidal behaviors.

The primary objective of this study is: To examine the fit of an Structural Equation Model (SEM) of risk-taking and suicidal behaviors and ideation, and explain those self-destructive behavior can possibly affected by Perceived Burdensomeness (PB) and Thwarted Belongingness (TB), Impulsivity and Suicidal Ruminations (SR) among with suicidal ideations.

This study will address the following secondary objectives:

  1. To explore the mediating effect of risk-taking, as a behavioral variable, on the relationship between suicidal ideation and behavior and impulsivity.
  2. To explore the mediating effect of risk-taking, as a self-reported variable, on the relationship between suicidal ideation and behavior and impulsivity.
  3. To explore the mediating effect of risk-taking, as a cognitive variable, on the relationship between suicidal ideation and behavior and impulsivity.
  4. To explore the mediating effect of PB on the relationship between SR and suicidal ideation and behavior.
  5. To explore the mediating effect of TW, on the relationship between SR and suicidal ideation and behavior.
  6. To explore the mediating effect of SR on the relationship between suicidal ideation and behavior and impulsivity.

The effect of developmental status (adult versus adolescent), will be considerated as a co-variate.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
12 Years 至 65 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 12-65 years
  • Adolescent population considered as at risk in mental health : admitted to the peadiatric department (CHMS).
  • or - Adult population : user of the Espoir73 association (an association for adults with a mental health problem) or users of SM@RT (CHS, a psycho-social rehabilitation center for adults with a mental illness).

排除标准

  • - No suicidal ideation or behaviors (none " Yes " response at the 6 questions of the C-SSRS screen version).

研究组 & 干预措施

Procedure based on questionnaires and a computer task

Experimental

This study begins with an initial screening phase. Only individuals exhibiting suicidal ideation and/or behavior, as identified by at least one affirmative response out of six on the C-SSRS scale (Posner et al., 2011), will be eligible to proceed with the study.

Subsequently, they will complete seven questionnaires and one computer task:

  • Risk-taking behaviors via a computer task via the Balloon Analogue Risk Task (BART, Lejuez et al., 2002, 2007) and questionnaires (NRTB and PRTB, Duell et al., 2020; Fryts et al., 2024)
  • Decision-making styles (GDMS, Scott and Bruce, 1995)
  • Impulsivity (UPPS-Short, Billieux et al., 2012)
  • Depressive symptoms (CES-D, Fuhrer and Rouillon, 1989)
  • Interpersonal needs (INQ, Landrault et al., 2019)
  • Suicidal ruminations (SRS, Rogers et al., 2022)

干预措施: Risk-taking variables (Other)

Procedure based on questionnaires and a computer task

Experimental

This study begins with an initial screening phase. Only individuals exhibiting suicidal ideation and/or behavior, as identified by at least one affirmative response out of six on the C-SSRS scale (Posner et al., 2011), will be eligible to proceed with the study.

Subsequently, they will complete seven questionnaires and one computer task:

  • Risk-taking behaviors via a computer task via the Balloon Analogue Risk Task (BART, Lejuez et al., 2002, 2007) and questionnaires (NRTB and PRTB, Duell et al., 2020; Fryts et al., 2024)
  • Decision-making styles (GDMS, Scott and Bruce, 1995)
  • Impulsivity (UPPS-Short, Billieux et al., 2012)
  • Depressive symptoms (CES-D, Fuhrer and Rouillon, 1989)
  • Interpersonal needs (INQ, Landrault et al., 2019)
  • Suicidal ruminations (SRS, Rogers et al., 2022)

干预措施: Psychological Processes (Other)

Procedure based on questionnaires and a computer task

Experimental

This study begins with an initial screening phase. Only individuals exhibiting suicidal ideation and/or behavior, as identified by at least one affirmative response out of six on the C-SSRS scale (Posner et al., 2011), will be eligible to proceed with the study.

Subsequently, they will complete seven questionnaires and one computer task:

  • Risk-taking behaviors via a computer task via the Balloon Analogue Risk Task (BART, Lejuez et al., 2002, 2007) and questionnaires (NRTB and PRTB, Duell et al., 2020; Fryts et al., 2024)
  • Decision-making styles (GDMS, Scott and Bruce, 1995)
  • Impulsivity (UPPS-Short, Billieux et al., 2012)
  • Depressive symptoms (CES-D, Fuhrer and Rouillon, 1989)
  • Interpersonal needs (INQ, Landrault et al., 2019)
  • Suicidal ruminations (SRS, Rogers et al., 2022)

干预措施: Suicidal ideation and behavior (Other)

结局指标

主要结局

Suicidal ideation and behaviors

时间窗: At inclusion

C-SSRS score (screen version) out of 6

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (6)

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