NCT05772364已完成不适用
Metabolic Response to the Consumption of Waters With Different Calcium Content: a Cross-over Clinical Study
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio2 个研究点 分布在 1 个国家目标入组 41 人开始时间: 2023年3月2日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- Change of blood calcium levels
研究概览
简要总结
The experimental study investigates which metabolic responses of calcium and parathyroid hormone are observable in blood and urine in a cohort of 41 healthy adults following a sequence of different exposures: low-calcium water first and high-calcium water afterward.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Body mass index ≥ 18 and < 30
- •Maintenance of diet and physical activity lifestyle throughout the duration of the study
- •Acceptance of informed consent
排除标准
- •Consumption of water with calcium > 150 mg/L
- •Pregnancy (as established by self-declaration), breastfeeding, menopause
- •Inability to follow the study protocol
- •Cardiac, vascular, renal, and oncological disease
- •Neuropsychiatric disease, developmental disorders
- •Disease or past surgery affecting the gastrointestinal tract
- •Drugs that interfere with bone (e.g. corticosteroids) or with fluid balance (e.g. diuretics)
研究组 & 干预措施
Low-calcium water first, then high-calcium water
Experimental
Participants drink 1.5 L of the designated water
干预措施: Loading of low-calcium water first, then high-calcium water (Other)
结局指标
主要结局
Change of blood calcium levels
时间窗: Baseline and 2.5 hours
Change of calcium levels (mg/dL) from baseline and after 2.5 hours
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
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