Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism
Completed
- Conditions
- Pseudohypoparathyroidism
- Registration Number
- NCT00004661
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Brief Summary
OBJECTIVES:
Determine the relationship between serum calcium concentrations and parathyroid hormone secretion in patients with pseudohypoparathyroidism.
- Detailed Description
PROTOCOL OUTLINE:
Patients are tested for parathyroid hormone response following sequential graded intravenous infusions of sodium citrate and calcium gluconate. Assays include ionized calcium and intact parathyroid hormone.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie PTH secretion dysregulation in pseudohypoparathyroidism patients studied in NCT00004661?
How does calcium gluconate infusion affect PTH levels compared to standard calcium supplementation in pseudohypoparathyroidism?
Are specific biomarkers identified in NCT00004661 for predicting PTH response to calcium infusions in pseudohypoparathyroidism?
What adverse events are associated with sodium citrate and calcium gluconate infusions in pseudohypoparathyroidism trials?
How do findings from NCT00004661 relate to other PTH-regulation therapies for pseudohypoparathyroidism and related endocrine disorders?