Real-World Characteristics, Treatment Patterns, and Clinical Outcomes in Contemporary Patients With Metastatic Castration-Resistant Prostate Cancer in the PRECISION Data Platform
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 17,111
- 试验地点
- 1
- 主要终点
- Number of Patients by Prior Therapies
研究概览
简要总结
The aim of this study is to assess treatment patterns, clinical outcomes, and patient characteristics among adults with metastatic castration-resistant prostate cancer (mCRPC) in the United States (US) real-world clinical practice. This study will be conducted using data extracted from the PRECISION (PRostatE Cancer dISease observatION) data platform.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 115 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of mCRPC between 01 January 2021 and 31 December
- •Male sex at index, where index is the date of initial mCRPC diagnosis.
- •Age 18 years at index.
排除标准
- 未提供
研究组 & 干预措施
mCRPC Cohort
Adult male patients with a recent diagnosis of mCRPC in PRECISION.
结局指标
主要结局
Number of Patients by Prior Therapies
时间窗: Baseline
Number of Patients by Number of Post-index Lines of Therapy (LOTs)
时间窗: Up to approximately 5 years
Number of Patients by Type of Therapy at Each LOT
时间窗: Up to approximately 5 years
Percentage of Patients Switching From One Type of Therapy to Another at Each LOT
时间窗: Up to approximately 5 years
Time to First-line (1L) Treatment Initiation (TTTI)
时间窗: Up to approximately 5 years
Time from index date (mCRPC diagnosis) to the start of 1L treatment.
Time to Next Therapy (TTNT) for Each LOT
时间窗: Up to approximately 5 years
Time from the end of each LOT to initiation of the next LOT.
次要结局
- Age(Baseline)
- Number of Patients by Patient Characteristics(Baseline)
- Progression-free Survival (PFS) From Index Date(Up to approximately 5 years)
- PFS From Each LOT(Up to approximately 5 years)
- Overall Survival (OS) From Index Date(Up to approximately 5 years)
- OS From Each LOT(Up to approximately 5 years)