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临床试验/NCT07016945
NCT07016945招募中不适用

Reactions to Experiencing Distress (RED) Study

University of Louisville1 个研究点 分布在 1 个国家目标入组 270 人开始时间: 2024年7月25日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
270
试验地点
1
主要终点
Free viewing task

研究概览

简要总结

The goal of this study is to understand whether race-related stress can impact the way people direct their attention and what interventions may be helpful for attention.

详细描述

Race-related stress is a public health problem and a known predictor of severe psychological symptoms in Black Americans. Although there is a strong link between race-related stress and adverse mental health outcomes, limited research has examined the transdiagnostic mechanisms that explain how experiencing race-related stress contributes to psychological symptoms or what interventions might effectively target these mechanisms. The scientific premise of this study is that race-related stress may contribute to disproportionate allocation of attention toward threatening stimuli (i.e., attention bias to threat), a known predictor of stress-related symptoms. This attentional bias may be modifiable through a brief, culturally-informed mindfulness intervention.

Racial identity is hypothesized to be a key individual difference factor that influences the extent to which race-related stress affects attention bias to threat, as well as the degree to which a mindfulness intervention can mitigate these biases. The study will recruit 200 Black adults from the community who have experienced race-related stress to participate in a laboratory study targeting three specific aims:

To use eye-tracking methods to examine whether race-related stress (compared to non-race-related stress) leads to greater attention bias to threat;

To test whether a brief mindfulness meditation (compared to a neutral audio condition) reduces attention bias to threat;

To investigate whether racial identity moderates (a) the effect of the race-related stress manipulation on attention bias to threat and (b) the efficacy of the mindfulness intervention in reducing attention bias to threat.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Eligibility for this study will include a positive response to the following questions: 1) Do you identify as Black or African American? 2) Have you ever in your lifetime personally experienced or witnessed another person experience any acts of racism or racial microaggressions? 3) Are you willing to complete a 1.5-hour study at the University of Louisville in the next 2 weeks? 4) Are you 18 or older?

排除标准

  • 未提供

研究组 & 干预措施

Main sample

Experimental

Participants are randomized to experimental and intervention conditions. They are either in: race stress/mindfulness, race stress/control audio, control stress/mindfulness, or control stress/control audio.

干预措施: Stress and Mindfulness Intervention (Behavioral)

结局指标

主要结局

Free viewing task

时间窗: 10 minutes

Free Viewing Task. This is the outcome measure for both manipulations listed above. To assess attention bias to threat, we will use a free-viewing task in which participants are instructed to freely view a pair of images side by side across two blocks of 60 trials each. In Block 1, participants will view two types of image pairs: one threatening (i.e., angry face) and one neutral (i.e., neutral facial expression) or both neutral.

Affect

时间窗: 5 minutes

To ensure that the manipulations outlined above are having the intended effect (increase in NA/ decrease in PA after stress manipulation and the opposite after the mindfulness manipulation), participants will complete the 20-item PANAS after each manipulation. The items ask participants to indicate how they are feeling in the moment in terms of both negative affect (e.g., distressed, interested) and positive affect (e.g., strong, inspired) on a scale of 1 (very slightly or not at all) to 5 (very much). Scores are summed to create a total negative affect and positive affect score.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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