NCT06765811已完成不适用
Identification of Rapid Kidney Function Decline in Older Adults with Different Types of Aging
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,539
- 试验地点
- 1
- 主要终点
- A ≥30% decline in glomerular filtration rate (GFR) within 2 years, i.e. a rapid decline in renal function
研究概览
简要总结
This observational study investigates whether a single set of GFR and urine albumin-to-creatinine ratio (ACR) thresholds can accurately screen for rapid kidney function decline in different elderly groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than 70 years;
- •GFR data measured at least twice (two years apart) and ACR data measured once (at baseline);
- •A clear record of the cause of the previous visit; from this, people diagnosed with kidney disease were selected, and kidney disease was defined as various primary nephritis, secondary nephropathy, acute kidney injury (AKI), chronic kidney disease, kidney tumors, or a diagnosis of proteinuria alone.
- •Signed informed consent form.
排除标准
- •People with missing baseline biochemical data;
- •Outliers in the population indicators, i.e., data deviating from the mean ± three times the standard deviation;
- •Data with significantly abnormal baseline renal function follow-up (abnormally elevated GFR by more than 10% within 2 years or abnormal ACR value as determined by consultation with a senior nephrologist).
结局指标
主要结局
A ≥30% decline in glomerular filtration rate (GFR) within 2 years, i.e. a rapid decline in renal function
时间窗: The risk of rapid decline in kidney function in the elderly was assessed during a 2-year follow-up period
次要结局
未报告次要终点
研究者
研究点 (1)
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