A Study of Cardiac Phenotypes in Sepsis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- To determine the prevalence of various cardiac manifestations in patients diagnosed as sepsis in order to understand specific treatment provided depending on cardiac outcomes.
研究概览
简要总结
The proposed study involves obtaining ethical clearance and informed consent before conducting a prospective, longitudinal investigation into sepsis among ICU patients. It will recruit patients diagnosed with sepsis using the SOFA score, focusing on those admitted under general medicine. Data collection will include medical history, laboratory results, and clinical assessments. Echocardiography within 24 hours of admission will evaluate cardiac function, with particular attention to indicators of distributive or hypodynamic shock. RV dysfunction will be assessed using TAPSE, and the IVC diameter will be measured. Patient safety and confidentiality will be paramount throughout the study. Follow-up will continue for 28 days post-admission to monitor patient outcomes.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients diagnosed to have sepsis by sepsis 3 guidelines and seeking treatment for the same at kasturba Medical College under General Medicine Department.
排除标准
- •Pre-existing Valvular Heart Disease/ Pre-existing Congenital Heart Disease/ Pregnancy/ Atrial Fibrillation/Cardiac arrest within 48 hours of presentation/ Ascites/ Pneumothorax.
结局指标
主要结局
To determine the prevalence of various cardiac manifestations in patients diagnosed as sepsis in order to understand specific treatment provided depending on cardiac outcomes.
时间窗: 24 hours,28 days
次要结局
- To draw comparison between various cardiac phenotypes through deranged(clinical parameters,prognosis and mortality rates.)
研究者
Rajika Khanna
Kasturba Medical College Manipal