Exploration of Pupil Dilation in Horner's Patients Taking Flomax
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- Pupil Size Measurements
研究概览
简要总结
This study is evaluating the pupil dilation of Horner's Patients who have ever taken an alpha blocker such as Tamsulosin. Patients will undergo eye dilation as would occur at a yearly eye examination, but their pupil dilation measurements will be recorded.
详细描述
This study will enroll 10 participants who have a unilateral Horner's Syndrome AND have a history of taking an alpha blocker such as Tamsulosin. Participants will be recruited based on those two enrollment criteria, and after consenting they will undergo pupil dilation with 10% phenylephrine. Once fully dilated the pupil size will be measured. Pupil dilation size of the eye affected by the Horner's Syndrome will be compared to the eye not affected by Horner's. Primary study outcome is the comparative dilation size of the Horner's affected eye to the non affected eye in all subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Horner's Syndrome
- •History of taking an alpha blocker (tamsulosin/ terazosin/doxazosin/alfuzosin/silodosin) medication
排除标准
- •Subjects with untreated hypertension
- •Subjects with thyrotoxicosis
- •Pregnant women
- •Inability to consent
- •Subjects with anatomical narrow angles who have never had a dilated exam
研究组 & 干预措施
10% phenylephrine
All patients will receive 10% phenylephrine at their eye examination as the drug to dilate the pupil. After pupil dilation, pupil size will be measured.
干预措施: 10% phenylephrine (Drug)
结局指标
主要结局
Pupil Size Measurements
时间窗: 20-30 minutes after 10% phenylephrine has been placed in each eye.
pupil dilation measurements will be taken of each eye at the eye examination.
次要结局
未报告次要终点
研究者
Cristos Ifantides, MD, MBA
Associate Professor, Department of Ophthalmology
Denver Health and Hospital Authority