NCT02333708Unknown不适用
Study of Circulating Microparticles in Giant Cell Arteritis
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Level of microparticles in the blood of patients with histologically proven giant cell arteritis.
研究概览
简要总结
To demonstrate that microparticles (MPs), having a powerful procoagulant potential, are in larger amounts in the blood of patients with histologically proven giant cell arteritis (GCA), compared with patients matched for age, sex and with or without inflammatory syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Men and women ≥ 18 years of age Patient affiliated to social security regimen
- •Informed and having signed the consent form to take part in the study.
- •Diagnosis of GCA, meeting at least 3 of the following 5 American College of Rheumatology (ACR) criteria for the diagnosis of GCA, including inflammatory syndrome and having
- •Either temporal artery biopsy showing characteristic GCA abnormality
- •Or inflammatory arteritis on imaging examination
排除标准
- •Persons under protection of the court or guardianship
- •Inability to understand or to follow study procedures
- •cancer diagnosed within the previous 5 years (except for non-melanoma skin cancer or in situ carcinoma of the cervix)non-contributory or inconclusive temporal artery biopsy
- •Any conditions that might interfere with MPs level: diabetes, recent endo-arterial gesture, current treatment with corticosteroids.
- •Participation in another ongoing clinical trial Current anticoagulant therapy
- •Active infectious disease
结局指标
主要结局
Level of microparticles in the blood of patients with histologically proven giant cell arteritis.
时间窗: Baseline
Level of microparticles (MPs) in the blood of patients with histologically proven giant cell arteritis (GCA), compared with patients matched for age, sex and with or without inflammatory syndrome.
次要结局
未报告次要终点
研究者
研究点 (1)
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