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临床试验/CTRI/2024/07/071038
CTRI/2024/07/071038尚未招募2/3 期

Randomized Clinical Study Of Virechan Karma And Narikel Khand Pak In Amlapitta With Special Reference To Hyperacidity

LRP Ayurvedic Hospital And Research Centre1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年8月2日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
80
试验地点
1
主要终点
To Study The Effect Of Virechan Karma And Narikel Khand Pak In Amlapitta

研究概览

简要总结

Amlapitta can be included under the broad heading of Gastro Esophageal Reflux Disease. Now in present era, due to bad food habits & faulty lifestyle.It becomes a burning problem in India and also all over the world.It is characterized by Amloudgara (sour, bitter rush) Hritkanthadaha (burning sensation in chest), Utklesh (vomiting), Avipak (indigestion), Aruchi (anorexia), klama (fatigue) ,Nil pitta Varna and Gandha yuktta Malapravrutti, Mandagni indicating the vikriti of pachak pitta along with kledak kapha and saman vayu. Amlapitta was first describe by Acharya Kashyapa in detail with separate chapter . In ancient classical textbook Charak Samhita Amlapitta was describe with its causes and pathogenesis. According to Ayurveda Amlapitta is divided in two types Urdhavaga Amlapitta and Adhoga Amlapitta.This disease can be corelated with Hyperacidity base on the clinical features. Hyperacidity is a disease occuring due to improper diet,lifestyle and improper digestion. Patient with Hyperacidity have signs & symptoms such as heart burn, chest pain, gastric discomfort, abdominal distention, sour blenching, food regurgition, nausea & reduced appetite. The annual death rate was 0.20/100,000. The causes were hemorrhagic reflux esophagitis in 51.9%,Aspiration pneumonia in 34.6%, perforation of esophageal ulcer in 9.6%, and spontaneous esophageal rupture with reflux esophagitis in 3.9%. Shodhan and shaman both treatments are mentioned for Amlapitta. Shodhan can rule out excessive vikrit doshas.In Shaman chikitsa mainly tikta rasa Pradhan pachak aushadhis and Kapha-pittaghna chikitsa should be given. Recurrence of Vikrit doshas is not possible with shodhan purvak shaman chikitsa. It may reoccur if only shaman chikitsa have operated. So, shaman treatment after the shodhan procedure is more reliable than either shaman or shodhan treatment.  Though Amlapitta is mainly associated with pitta doshas and the excellent treatment for pitta dosha is virechan. Associated in this disease, therefore for complete irradiation from this disease. Acharya Chakradatta narrated to give virechan karma according to patients bala (strength)4 . The drug Narikel Khand Pak is selected for the shaman chikitsa which has Tikta Katu and madhur ras pradhan dravyas and have Agnidipan, Pachan and Pitta doshahara Vatakaphahar properties.Though to study efficacy of this drug in Amlapitta Narikel Khand Pak is selected.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patient will be selected irrespective of gender occupation and habitat.
  • 2.Those who are fit for virechan procedure.
  • 3.Patients presenting with classic sign and symptoms of Amlapitta.

排除标准

  • 1.Age below 20 years and above 60 years.
  • 2.Those who are not fit for Virechan procedure.
  • 3.Patient having history of hyper acidity due to secondary underling cause like oesophageal carcinoma.
  • 4.Patients diagnosed with gastric and duodenal ulcer.

结局指标

主要结局

To Study The Effect Of Virechan Karma And Narikel Khand Pak In Amlapitta

时间窗: 48 days

次要结局

  • To Reduce the Almapitta in 48 days(To study the literature related to concept of Amlapitta)

研究者

发起方
LRP Ayurvedic Hospital And Research Centre
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Akshaykumar Mote

LRP Ayurvedic medical college and hospital

研究点 (1)

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