跳至主要内容
临床试验/CTRI/2025/03/081967
CTRI/2025/03/081967尚未招募2 期

Clinical Evaluation of Virechan Karma of Aragwadhadi Avaleha in the Management of Hypertension

Dr Bidushi Mishra1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年4月1日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Reduction in Lipid profile level.

研究概览

简要总结

According to World Health Organization (WHO), India is going to have most of the lifestyle disorders in the near future.It is estimated that 600 million people are affected worldwide with Hypertension. Hypertension results from a variety of reasons like stress, obesity, genetic factors, over use of the salts in the diet and ageing.It is a chronic non communicable disease in which the pressure exerted by the blood on the wall of the artery is elevated.It is defined as a persistent elevation of systolic Blood Pressure above 140 mmHg and diastolic pressure above 90mmHg.In Ayurveda Charak clearly describes that vyana vayu,a component of vata dosha is said to be responsible for various kinds of movement in the body.With the help of vyana vayu,heart contracts and propels blood continuously all over body so it suggests the involvement of vyana vayu in regulation of blood pressure.In modern medicine lots of drugs are available for controlling blood pressure but they have some side effect, Hence people are looking towords ayurvedic treatment.

Previously Hypertentionis studied in various ways. From those study we can state that Virechan karmacan be found impressively effective in the treatment of Hypertention. Aragwadha is the drug of choice as a Mrudu Virechak that is not only beneficial for adults but is safe even for children.It act as Madhura,Tikta,Katu                  Kashaya Rasa having Tridoshashamaka properties which helps in reducing hypertension by removing Margavarodha and daily elimination of excess morbid toxic materials from the body through Adhobhaga by the predominance of Jala and Prithvi Mahabhutas.Thereby it helps in pacifying kapha and pitta Doshas and simultaneously having its effect on Rakta and regulates the activity and movement of Vata Dosha by its anulomana action.Virechana helps to decrease the fluid volume which reduces the cardiac output,subsequently corrects the Rasa,Rakta Samvahana and helps to reduce the Hypertension.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients diagnosed with Hypertension.
  • 2.Newly diagnosed patients having six month duration of stage 1 Essential Hypertension SBP(150-160mmHg)or DBP(90-100mmHg)of either sex between the age group of 18 to 60 years were include in this Research project.

排除标准

  • 1.Patient having Stage 2 Hypertension with SBP(Greater than 180mmHg)or DBP(Greater than 110 mmHg).
  • 2.Patient having Stage 1 Essential Hypertensionwith less than six months of durations.
  • 3.Patients contraindicated for Virechan that are Bleeding hemorrhoids,chronic fissure in ano and irritable bowel syndrome.

结局指标

主要结局

Reduction in Lipid profile level.

时间窗: Base Line 30th day,60th day

次要结局

  • Reduction in signs and symptoms of Hypertension(Base Line 30th day,60th day)

研究者

发起方
Dr Bidushi Mishra
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Bidushi Mishra

Bharati Vidyapeeth College Of Ayurved Pune

研究点 (1)

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